primary immunodeficiencies (pid) are a group of disorders, characterized by an unusual susceptibility to infections. delay in diagnosis results in increased morbidity and mortality in affected patients. the purpose of this study was to determine the mortality rate of iranian immunodeficient patients referred to children medical center hospital affiliated to tehran university of medical sciences...

INTRODUCTION Common variable immunodeficiency encompasses a group of heterogeneous conditions linked by a lack of immunoglobulin production and primary antibody failure. Although primary immunodeficiencies are typically characterized by recurrent infections, autoimmune manifestations have increasingly been recognized. Neurological complications are extremely rare and to the best of our knowledg...

Backgroup: selective IgA deficiency is the most frequent primary immunodeficiency worldwide. Patients are usually asymptomatic. However, those cases with symptoms develop recurrent infections and increased risk of autoimmune malignant diseases. On other hand, rheumatic disorders uncommon during childhood juvenile idiopathic arthritis as common one. Case Presentation: we present case a female pa...

Primary and secondary immunodeficiency disorders are a diverse group of illnesses resulting from one or more abnormalities of the immune system. The clinical manifestations include increased susceptibility to infection and an increased risk for autoimmune disease and malignancy. Primary immune deficiency (PID) diseases are a group of serious disorders arising from an intrinsic defect in the imm...

Abstract The immune system is a particularly sophisticated protection system. As true guardian of our health, the defends body against external or internal aggressions. Sometimes, not able to fight because it lacks does function properly causing an ineffective absent response. Although more than 400 diseases exist, there no data available in country. We analyze through retrospective study carri...