There is now considerable evidence that inflammatory cytokines such as interleukin-1 (IL-1) and tumour necrosis factor play a major role in chronic inflammatory diseases such as rheumatoid arthritis (RA) [ 11, the main site of which is the synovial lining of joints. Within the synovium, cells such as macrophages, fibroblasts and endothelial cells are capable of producing 1L-1 and TNF [ l ] and ...

PURPOSE This study was undertaken to investigate the effects of gamma linolenic acid (GLA) on inflammation and extracellular matrix (ECM) synthesis in mesangial and tubular epithelial cells under diabetic conditions. MATERIALS AND METHODS Sprague-Dawley rats were intraperitoneally injected with either a diluent [n=16, control (C)] or streptozotocin [n=16, diabetes (DM)], and eight rats each f...

OBJECTIVE Premenstrual syndromes (PMS) affecting 20-40% of women of reproductive age. The aim of this double blind and placebo controlled trial was to investigate whether femicofort a supplement contains Vitamin B6, Vitamin E and evening primrose oil could relieve symptoms of PMS. METHOD This was a randomized and double blind clinical trial. The trial was conducted between November 2009 and A...

Numerous reports in the medical literature and popular media have discussed the effectiveness of various nonhormonal agents in reducing menopausal hot flash symptoms. Data for these therapies are limited, and most of the studies have been conducted in women with a history of breast cancer. Selective serotonin reuptake inhibitors and venlafaxine have been shown to reduce hot flashes by 19 to 60 ...

Zinc is an important co-factor for metabolism relevant to neurotransmitters, fatty acids, prostaglandins, and melatonin, and indirectly affects dopamine metabolism, believed intimately involved in attention-deficit/hyperactivity disorder (ADHD). To explore the relationship of zinc nutrition to essential fatty acid supplement and stimulant effects in treatment of ADHD, we re-analyzed data from a...

817 configuration.A similar meiotic structure occurs in a few disparate organisms, such as evening primrose and termite, but it has not been seen before in vertebrates. Grützner and colleagues have created fluorescent ‘paints’ for individual platypus chromosomes. By tagging the chromosomes in this manner, they could determine the number of copies of each chromosome in males and females,and thei...