Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by xenobiotic inducers of cytochromes P450 is part of a pleiotropic response that includes liver hypertrophy, tumor promotion, effects on lipid homeostasis, and energy metabolism. Here, we describe an acute response to CAR and PXR activators that is associated with induction of Insig-1, a protein with antilipogen...

developing countries (6, 8). The higher probability of car deficiency in developing countries probably requires operating vehicle allocation before mode choice. Car-deficient households are households where the number of drivers exceeds the number of cars. Moreover, three types of private vehicles (car, motorcycle, and bicycle) should be considered in the vehicle allocation step in households b...

With the development of car-hailing industry, it has become an indispensable way travel in our lives. Accurate prediction online demand can provide basis for real-time vehicle dispatch and dynamic pricing companies. Most previous studies on forecasting have only considered temporal spatial factors separately, while effects time series not been considered. In this paper, temporal, spatial, weath...

Higher density reduces distances, private car dependency and thus reduces greenhouse gas emissions (GHGs). As a result, increased density has been given a central role among urban development targets. However, it is not just travel behavior that changes along with density. Rather, the consumption patterns, or overall lifestyles, change along with changing urban structure, particularly with chan...

Increasing private car ownership and dependency has led to a low share of walking as an active mode well congestion, air pollution, health problems in developing countries. This paper aims identify compare the impacts selection socio-economic, travel-related, built environment variables on likelihood respondents’ sensitivity distance, both for discretionary mandatory trips. The analysis drew it...

This paper proposes a new model to estimate the mean and covariance of stochastic multi-class (multiple vehicle classes) origindestination (OD) demands from hourly classified traffic counts throughout the whole year. It is usually assumed in the conventional OD demand estimation models that the OD demand by vehicle class is deterministic. Little attention is given on the estimation of the stati...

Australia’s first Mobility as a Service (MaaS) trial commenced in April 2019 Sydney, running for two years. The objective of the is at least twofold – to assess interest various MaaS subscription plans through bundling public transport, rideshare, car share and rental with varying financial discounts monthly fees, contrast pay you go (PAYG); extent which use private might change following mobil...