Article history: Received 8 March 2007 Received in revised form 14 October 2009 Accepted 20 October 2009 Available online xxxx JEL classification: D24 L63 L86

I this paper we characterize the impact of production technology on the optimal product line design. We analyze a problem in which a manufacturer segments the market on quality attributes and offers products that are partial substitutes. Because consumers self-select from the product line, product cannibalization is an issue. In addition, the manufacturer sets a production schedule in order to ...

In today’s global economy manufacturing companies are continuously re-evaluating their location. In many instances companies decide to relocate some or all of their manufacturing activities to so called low labor cost countries. However, the perception that this is cost effective is not always correct. In many instances the costs of producing in low labor cost countries are highly under estimat...

Hybridomas are cells that have been engineered to produce a desired antibody in large amounts. To produce monoclonal antibodies, Bcells are removed from the spleen of an animal that has been challenged with the relevant antigen. These B-cells are then fused with myeloma tumor cells that can grow indefinitely in culture (myeloma is a B-cell cancer). This fusion is performed by making the cell me...

Despite a growing population and increasing demands of that population for improved diets, it appears that the world is not close to universal famine (3, 53). There is enough food now produced to feed the world's hungry (54). That people are malnourished or starving is a question of distribution, delivery, and economics, not agricultural limits. The problem is putting the food where the people ...

Benedenia disease caused by the ectoparasite Benedenia seriolae is a serious parasitic disease in yellowtail aquaculture, leading to secondary viral or bacterial infections. Benedenia disease is difficult to prevent in marine aquaculture systems. To evaluate the genetic basis of Benedenia disease resistance in yellowtail, a genome-wide and chromosome-wide linkage analysis was initiated using F1...