The ability of three isolates of serogroup 1 and one isolate of serogroup 4 of Legionnaires' disease bacterium (LDB) to infect and cause fever and death in guinea pigs was studied, as well as their ability to produce plaques in cultured primary chick embryo cells. The serogroup 4 isolate originally was recovered from cord clot and placental tissue from a healthy mother following delivery of a n...

Several species of the genus Borrelia exhibit antigenic variation of variable major proteins on their surface during relapsing fever. We have investigated the African relapsing fever species Borrelia crocidurae during infections in mice and compared it with the thoroughly studied North American species Borrelia hermsii. A major difference between the two species is that B. crocidurae can bind a...

Q fever is a bacterial infection affecting mainly the lungs, liver, and heart. It is found around the world and is caused by the bacteria Coxiella burnetii. The bacteria affects sheep, goats, cattle, dogs, cats, birds, rodents, and ticks. Infected animals shed this bacteria in birth products, feces, milk, and urine. Humans usually get Q fever by breathing in contaminated droplets released by in...

Abstract Background The impact of COVID-19 has been devastating on a global scale. negative conversion time (NCT) SARS-CoV-2 RNA is closely related to clinical manifestation and disease progression in patients. Our study aimed predict factors associated with prolonged NCT mild/moderate Methods features, laboratory data treatment outcomes patients were retrospectively analyzed. Then univariate m...

The purpose of this study was to investigate whether an age-associated impaired acute-phase response exists. Nine healthy elderly volunteers (median, 66 years; range, 61 to 69 years) and eight young controls (median, 24 years; range, 20 to 27 years) were given an intravenous bolus of endotoxin (2 ng/kg). The rectal temperature was monitored continuously, and blood samples for cytokine measureme...

Typhoid fever is a systemic prolonged febrile illness caused by a bacteria Salmonella typhi. The disease is transmitted through ingestion of food or water contaminated with faeces or urine of infected persons. Acute typhoid fever is characterized by prolonged fever, disturbances of bowel functions (constipation or diarrhoea), headache, malaise and anorexia. Cough is common in the early stage of...