New therapies are incorporated into clinical practice for a variety of reasons. Usually, they are more efficacious than what is currently used for a specific disease state. Sometimes, they are just as efficacious but safer. When a new treatment strategy is able to achieve better efficacy and safety, at an equal or lower cost, it becomes a “dominant” strategy. Few therapies in cardiovascular med...

Abstract Recent years have seen the rise of fittingness-first views , which take fittingness to be most basic normative feature, in terms other features can explained. This paper poses a serious difficulty for approach by showing that existing accounts cannot plausibly accommodate an important class reasons: reasons not believe proposition. There are two kinds proposition: considerations counte...