AIM OF THE STUDY Recent investigations have taken into account the role of mast cells in prostate cancer formation, analyzing their dual functions (as tumour growth promoters and tumour growth inhibitors). The aim of our study was to compare mast cell infiltration and microvessel density in prostate cancer and in benign prostate hyperplasia. We also attempted to find possible relationships amon...

Epidemiological studies have shown that one of the strongest risk factors for prostate cancer is a family history of the disease, suggesting that inherited factors play a major role in prostate cancer susceptibility. Germline mutations in BRCA2 predispose to breast and ovarian cancer with its predominant tumour suppressor function thought to be the repair of DNA double-strand breaks. BRCA2 has ...

PURPOSE With the aim of evaluating the clinical significance of systematic prostate biopsy before transurethral resection of the prostate (TUR-P), clinical data were reviewed retrospectively in patients who had underwent prostate biopsy prior to scheduled TUR-P. PATIENTS AND METHODS Between July, 1994 and June, 2000, TUR-P was scheduled in a total number of 456 patients with clinically diagno...

The aquaporin (AQP) families of water channels are intrinsic membrane proteins that facilitate selective water and small solute movement across the plasma membrane. The purposes of this study were to determine the expression and localization of AQPs in benign prostatic hyperplasia and prostate cancer. Prostatic tissue was collected from patients with benign prostatic hyperplasia or prostate can...

  Background and Objective: Non-specific granulomatous prostatitis is an uncommon diffuse inflammatory condition of the prostate. It is important because it may be mistaken for prostatic carcinoma. The aim of the study was to determine the prevalence of non-specific granulomatous prostatitis (NSGP) and comparing the results of transrectal ultrasonography, serum prostate specific antigen (PSA) ...

To investigate the clinical effect of transparent hose in treatment benign prostatic hyperplasia with bladder stones by transurethral resection prostate. A total 130 patients calculi were selected and divided into experimental group control 65 cases each group. Both groups treated The was for prostate cystoscopy. operation postoperative related indexes two compared analyzed. time, blood loss, s...

background and objective: non-specific granulomatous prostatitis is an uncommon diffuse inflammatory condition of the prostate. it is important because it may be mistaken for prostatic carcinoma. the aim of the study was to determine the prevalence of non-specific granulomatous prostatitis (nsgp) and comparing the results of transrectal ultrasonography, serum prostate specific antigen (psa) and...

[Purpose] To investigate the effect of pulsed electromagnetic field with or without exercise therapy in the treatment of benign prostatic hyperplasia. [Subjects and Methods] Sixty male patients aged 55-65 years with benign prostatic hyperplasia were invited to participate in this study. Patients were randomly assigned to Group A (n=20; patients who received pulsed electromagnetic field in addit...

Spontaneously hypertensive rats (SHRs), a commonly used model of genetic hypertension, exhibit features of glandular hyperplasia of the ventral prostate, including the narrowing of acini with epithelial protrusions into the lumen and the piling up of epithelial cells. These rats also have frequent urinary voiding. In order to define the fundamental processes that lead to prostatic hyperplasia i...

Prostatic inflammation is of considerable importance to urologic research because of its associationwith benign prostatic hyperplasia and prostate cancer. However, the mechanisms by which inflammation leads to proliferation and growth remain obscure. Here, we show that insulin-like growth factors (IGFs), previously known as critical developmental growth factors during prostate organogenesis, ar...