The absence of effective therapies for hormone refractory prostate cancer establishes the need to develop novel therapeutic modality, such as a gene therapy, that can be applied either separately or in conjunction with current treatment modalities for the treatment of advanced prostate cancer. About 80 protocols for prostate cancer gene therapy have been practiced since 1994. The gene therapy m...

Prostate cancer is the commonest cancer in Jamaica as well as the leading cause of cancer-related deaths. One report suggested that Jamaica has the highest incidence rate of prostate cancer in the world, with an age-standardised rate of 304/100,000 per year. The Caribbean region is reported to have the highest mortality rate of prostate cancer worldwide. Prostate cancer accounts for a large por...

Discordant results in preclinical and clinical trials have raised questions over the effectiveness of antioxidants in prostate cancer chemoprevention. Results from the large-scale Selenium and Vitamin E Cancer Prevention Trial (SELECT) showed that antioxidants failed to prevent, and in some cases promoted, prostate cancer formation in men without a history of the disease. One possible explanati...

Aim: to improve the outcomes of surgical treatment benign prostatic hyperplasia by bipolar transurethral resection based on personalized approach. Materials and methods. Surgical prostate was carried out in 50 patients: approach, that is extensive preoperative preparation, adopted 25 cases, standard procedure implemented rest cases. Functional were assessed 1, 3 6 months aft er surgery, taking ...

Prostate cancer treatment can significantly impact erectile function, and penile rehabilitation has been proposed to improve the impacts. However, effectiveness of rehabilitations after prostate is scarce. The aim this systematic review was evaluate different interventions program treatment. We conducted a comprehensive search electronic databases, PubMed Google Scholar, identify randomized con...

Testosterone is important growth factor for prostate cells. If testosterone availability drops, prostate cells stop thriving. Benign prostate shrinks and the same happens with prostate cancer cells. Larger decrease in testosterone availability means larger reduction in prostate cells mass. Although only reduction in testosterone levels will not, in most occasions, per‐ manently heal prostate ca...

BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. Furthermore, metastatic prostate cancer is genera...

This review discusses the current state of Targeted Alpha Therapy (TAT) in prostate cancer, particularly mCRPCT (metastatic castration-resistant cancer). describes widely used Radium-223 and novel trend TAT field with a special focus on prostate-specific membrane antigen (PSMA)-based alpha therapy. With this in-depth discussion growing PSMA-based therapy, we aim also to analyze most useful diag...

Prostate Cancer & diseases is quite common in elderly men. Early detection of prostate cancer is very essential for the success of treatment. In the diagnosis & treatment of prostate diseases, prostate boundary detection from sonography images plays a key role. However, because of the poor image quality of ultra sonograms, prostate boundary detection is still difficult & challenging task & no e...

Inspite of progress in diagnosis, treatment prostate cancer has become one of the most frequent lethal cancers in males. Rate of detection of prostate cancer varies widely across the world. Research on molecular biology of prostate cancer is expected to give new insight of improving, distinguishing slow growing from aggressive clinically relevant cancers and provide target for treatment. Tradit...