Pseudoexfoliation (PFX) is characterized by the abnormàl production and accumulation of a fibrillar extracellular material with a gray appearance in the anterior segment of the eye and other tissues of the body. It is the most common identifiable cause of open-angle glaucoma, and there is an etio1oical association between PFX and cataract formation. Complication rates for cataract surgery in ey...

PURPOSE To assess the association of LTBP2 mutations with primary angle closure glaucoma (PACG). METHODS We studied 54 unrelated patients with PACG and one individual with pseudoexfoliation accompanied with angle closure glaucoma; these consisted of 28 female and 27 male subjects aged 27 to 82 (mean, 63) years. The 36 exons and flanking intronic sequences of LTBP2 in all patients were amplifi...

Glaucoma is associated with an increased incidence of cardiovascular disease and risk factors. The aim of the study was to assess the left ventricular (LV) function in patients with pseudoexfoliation (PEX) glaucoma using doppler-echocardiographic examinations. Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed in 21 patients with (PEX) glaucoma and 24 controls...

Background/Aim. Impaired vision resulting from glaucoma can have deleterious effects on both physical and mental health. This study aims at examining the adverse impacts of primary open angle (POAG), closure (PACG) pseudoexfoliation (PEG) quality life (QOL). Methods. research, designed as a cross-sectional study, included 102 patients treated for POAG, PACG, or PEG. The were divided into three ...

PURPOSE Pseudoexfoliation (PEX) syndrome is a generalized elastic microfibrillopathy characterized by fibrillar deposits in intra- and extraocular tissues. Genetic and nongenetic factors are known to be involved in its etiopathogenesis. This study was focused on six functional candidate genes involved in PEX material deposition and the analysis of their potential association with PEX syndrome a...

PURPOSE The purpose of this study was to investigate the existence of pseudoexfoliation syndrome (PXF) as a risk factor for the development of central retinal vein occlusion (CRVO). METHODS This was a retrospective, comparative study of the prevalence of pseudoexfoliation in three groups of patients: 48 patients with CRVO, 164 patients with branch retinal vein occlusion (BRVO), and 70 control...

PurposeTo compare lamina cribrosa curvature (LCC) in pseudoexfoliation glaucoma (PXG) and primary open-angle (POAG) to elucidate the factors associated with LCC both groups.DesignRetrospective, cross-sectional study.MethodForty eyes PXG visual field mean deviation–matched 40 POAG were included. Spectral domain optical coherence tomography enhanced depth imaging was used acquire LC images. The i...