We report a case of a 34-year-old male who presented with an acute onset of pleomorphic psychiatric features. Upon examination we later diagnosed him with Gorlin-Goltz syndrome based on clinical and radiological findings that are characteristic for this rare autosomal dominant syndrome. His psychiatric manifestations included irritability, aggressive behavior, labile mood, hallucinations, paran...

It is now well recognized that as well as having a characteristic facial dysmorphology and a range of congenital abnormalities, individuals with chromosome 22q11 deletion syndrome (22q11DS) have a greatly increased risk of developing psychosis, in particular schizophrenia. The majority of deletions span a large 3Mb region at 22q11. However, the presence of affected individuals carrying smaller ...

OBJECTIVES To examine the intensity of monitoring received by important patient subgroups during high-risk periods (the 12 weeks after psychiatric hospitalization and after new antidepressant starts). DESIGN Retrospective secondary analysis of data from the Veterans Affairs (VA) National Registry for Depression using patients aged 65 and older receiving depression treatment from 1999 to 2004....

This article reviews the family foster care model practised in the small Belgian town of Geel. A historical introduction is followed by a description of a family foster care project in its current form. Issues are raised as to whether the current culture of care pathways, managed care, payment by results and an emphasis on 'cure' are conducive to recovery as promoted by the recovery model. Fina...

1: ‘I’ll tell you what I want, what I really, really want’ Sue Ashby, Lecturer, Keele University, & one of the older people from the research projectBackground: This paper unites the key learning following older people involvement as active members of a research steeringgroup evaluating and developing interprofessional working among health and social care staff working inintermediat...

An ex-patient draws on his own experience to suggest how life in mental hospital could be made more beneficial in simple ways and expresses reservations about the acceptance of patients back into the community.

Despite their size and complexity, mental hospitals have been scarcely touched by the management methods revolution of the last decade. The factors which complicate the use of new techniques in hospital management are not insurmountable.

INTRODUCTION The aim of this study was to investigate to what extent pathological creatine kinase (CK) levels are associated with aggressive behavior in patients admitted to psychiatric facilities. It is based on the assumption that CK activity increases prior to a rise in motor activity and aggressive behavior. It should be noted that this assumption requires additional confirmation in more ex...

INTRODUCTION Although mefloquine use is known to be associated with a risk of severe neuropsychiatric adverse reactions that are often preceded by prodromal symptoms, specific combinations of neurologic or psychiatric reactions associated with mefloquine use are not well described in the literature. This study sought to identify a distinct neuropsychiatric syndrome class associated with mefloqu...