Gastric electrical stimulation (GES) has been used to treat obesity with unclear mechanisms and limited parameter ranges. This study explores effects of GES parameters on ventral medial hypothalamic (VMH) activity, feeding, and body weight in diet-induced obese (DIO) rats. For experiment 1, discharge rates were recorded in 39 gastric distension-responsive (GD-R) neurons in 12 DIO rats. Basal ra...

Little is known about the efficacy of pulsed ultrasound compared with continuous ultrasound. Previous studies on the efficacy of pulsed ultrasound were not systematic and gave different results. In this study, the effects of pulse length, pulse interval, pulse length × pulse intervals, and treatment time on sonochemical activity were investigated using a simple oxidation of iodide method and a ...

Introdouction: Dentinal hypersensitivity (DH) is one of the most painful chronic problems reported in dental offices. Various methods have been applied for the treatment of DH. However, majority of them are either ineffective or last for a short period of time. It has been reported that lasers, particularly Neodymium- doped: Yttrium Aluminum Garnet laser (Nd: YAG), can be helpful in the treatme...

BACKGROUND Fingolimod (FTY-720) has shown efficacy in relapsing multiple sclerosis (MS), while some side effects of this drug have been recognized that the most important is cardiovascular side effects. The aim of this study was to evaluate the cardiovascular side effects of FTY-720. However, the effect of fingolimod on cardiac has not been well recognized. This study was designed to evaluate t...

The pattern of GnRH release is associated with differential synthesis and release of LH and FSH. Using a perifusion system, we previously reported that stimulation of the LbetaT2 cell line with varying GnRH pulse frequencies resulted in differential stimulation of LHbeta and FSHbeta gene transcription, analogous to previous observations in primary gonadotropes. In the present study, we investig...

The interaction of intense femtosecond x-ray pulses with molecules sensitively depends on the interplay between multiple photoabsorptions, Auger decay, charge rearrangement, and nuclear motion. Here, we report a combined experimental theoretical study ionization fragmentation iodomethane (CH_{3}I) by ultraintense (?10^{19}??W/cm^{2}) at 8.3 keV, demonstrating how these dynamics depend pulse ene...

Ionization processes limit the accelerating gradient and place an upper limit on the pulse duration of the electromagnetic driver in the inverse Cherenkov accelerator ~ICA!. Group velocity slippage, i.e., pulse lethargy, on the other hand, imposes a lower limit on the pulse duration. These limits are obtained for two ICA configurations in which the electromagnetic driver ~e.g., laser or millime...