1. Obstructive sleep apnoea and its variants often provoke hundreds of short arousals that lead to the most important symptom, disabling hypersomnolence. The measurement of sleep in these conditions requires the documentation of these short arousals and this is conventionally done by manual inspection of the sleeping EEG, a laborious procedure. 2. Other markers of 'arousal', that are easier to ...

objective: electroporation is the most common method used for the transfection of dna. although this method has been attributed for various cell using different buffer compositions, the effects of dna concentration on the transfection efficiency has not yet been studied. here the correlation between the efficiency of electroporation reaction and increments of dna concentration has been investig...

The current status of the Canadian Home Fitness Test is reviewed. This simple procedure was originally conceived for the mass testing of fitness levels and for home use as a motivational tool in exercise programmes. The test is carried out on a double 8 inch step (such as a domestic staircase) at an age and sex-specific rhythm set by a long-playing record. Fitness is assessed from a combination...

[This corrects the article DOI: 10.1371/journal.pone.0189150.].

OBJECTIVE To determine prevalence of Exercise-induced Bronchospasm (EIB) in hockey players, who had represented or were aspiring to represent Pakistan at international level. METHOD An observational, cross-sectional study was done on the prevalence of EIB in national hockey players of Pakistan. All participants of the training camp (n = 27) players were included in this study, after obtaining...

Background As part of the assessment of all medical patients, vital signs are registered. However, each vital sign on its own (e.g. blood pressure, respiratory rate, pulse or peripheral oxygen saturation) only provide parts of the picture and are not considered global markers of illness. Loss of independence (LOI) (e.g. ability to stand, get into bed or out of a chair unaided) has been proposed...