Port wine stains (PWS) are the most common vascular malformation of the skin, occurring in 0.3% to 0.5% of the population. Noninvasive laser irradiation with flashlamp-pumped pulsed dye lasers (selective photothermolysis) currently comprises the gold standard treatment of PWS; however, the majority of PWS fail to clear completely after selective photothermolysis. In this review, the clinically ...

In this paper method has been proposed to improve the precision of Personalized Web Search (PWS) using Trust based Hubs and Authorities(HA) where Hubs are the high quality resource pages and Authorities are the high quality content pages in the specific topic generated using HyperlinkInduced Topic Search (HITS). The Trust is used in HITS for increasing the reliability of HITS in identifying the...

Abnormal feeding behavior is one of the main symptoms of Prader-Willi syndrome (PWS). By studying a PWS mouse mutant line, which carries a paternally inherited deletion of the small nucleolar RNA 116 (Snord116), we observed significant changes in working-for-food behavioral responses at various timescales. In particular, we report that PWS mutant mice show a significant delay compared to wild-t...

objective prader-willi syndrome (pws) is a genetic syndrome presenting with severe hypotonia and decreased agility. growth hormone (gh), which is often used in these patients to treat short stature and obesity, seems improve hypotonia, physical strength, activity, and locomotor developmental ability. the aim of this study was to find the effects of growth hormone on agility and strength of thes...

background: subglottic stenosis is defined as inflammatory narrowing of the airway. it can be related to trauma, intubation, autoimmune disorders, vascular malformations, infection and congenital abnormalities. pot-wine stain (pws) is a small dermis venous malformation which is present at birth. pws is found on face and neck, but can occur in throat and can cause subglottic stenosis. case repor...

BACKGROUND Angelman syndrome (AS) and Prader-Willi syndrome (PWS) are 2 distinct neurodevelopmental disorders caused primarily by deficiency of specific parental contributions at an imprinted domain within the chromosomal region 15q11.2-13. Lack of paternal contribution results in PWS either by paternal deletion (approximately 70%) or maternal uniparental disomy (UPD) (approximately 25%). Most ...

BACKGROUND despite evidence of an obesity-related disability, there is a lack of objective muscle functional data in overweight subjects. Only few studies provide instrumental strength measurements in non-syndromal obesity, whereas no data about Prader-Willi syndrome (PWS) are reported. The aim of our study was to characterize the lower limb muscle function of patients affected by PWS as compar...

OBJECTIVE The aim of this study was to assess the prevalence of congenital defects observed in patients with Prader-Willi syndrome (PWS) and to compare this prevalence with that described in the general population. In addition, these findings were correlated with the different etiologic subtypes. METHODS A total of 180 children with PWS followed for 13 years were included in this study. Diagn...

Prader-Willi syndrome (PWS) is a genetic disorder in which hypotonia is the predominant feature in infancy, whereas developmental delay, obesity and behavioral problems become more prominent during childhood and adolescence. Sleep problems occur frequently among individuals with PWS. Because of the development of obesity, craniofacial dysmorphism and muscular hypotonia, patients with PWS are at...

CONTEXT Methylation changes observed in Prader-Willi syndrome (PWS) may impact global methylation as well as regional methylation status of imprinted genes on chromosome 15 (in cis) or other imprinted obesity-related genes on other chromosomes (in trans) leading to differential effects on gene expression impacting obesity phenotype unique to (PWS). OBJECTIVE Characterize the global methylatio...