viviane barros silva medicinal chemistry laboratory, pharmacy department, federal university of sergipe, são cristóvão, brazil daniele lima travassos medicinal chemistry laboratory, pharmacy department, federal university of sergipe, são cristóvão, brazil angelita nepel nuclear magnetic resonance laboratory, chemistry department, federal university of paraná, curitiba, brazil andersson barison nuclear magnetic resonance laboratory, chemistry department, federal university of paraná, curitiba, brazil emmanoel vilaça costa chemistry department, institute of sciences, federal university of amazonas, manaus, brazil luciana scotti biotechnology center, federal university of paraíba, campus i, joão pessoa, brazil