In the title compound, C(17)H(12)Cl(2)N(6)O(3), the 1H-1,2,3-triazole ring [maximum deviation = 0.003 (1) Å] forms dihedral angles of 34.08 (6) and 28.38 (6)°, respectively, with the nitro- and dichloro-substituted benzene rings. The dihedral angle between the benzene rings is 6.68 (5)°. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules into chains running parallel to the a axis.

In the title carbohydrazide, C10H7N3O4S, the dihedral angle between the terminal five-membered rings is 27.4 (2)°, with these lying to the same side of the plane through the central CN2C(=O) atoms (r.m.s. deviation = 0.0403 Å), leading to a curved mol-ecule. The conformation about the C=N imine bond [1.281 (5) Å] is E, and the carbonyl O and amide H atoms are anti. In the crystal, N-H⋯O hydroge...

This study describes the synthesis and vacuole-inducing activity of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carbohydrazide derivatives, including five potent derivatives 12c, 12 g, 12i, 12n, 12A that exhibit excellent activity. Remarkably, effectively induces methuosis in tested cancer cells but not human normal cells. In addition, exhibits high pan-cytotoxicity against different ...

A method was proposed for the synthesis of substituted 2-(2-(furan-2-carbonyl)hydrazono)-4-oxobutanoic acids by reaction 2,4-dioxobut-2-enoic with furan-2-carbohydrazide. It found that undergo intramolecular cyclization in presence propionic anhydride to form corresponding N'-(2-oxofuran-3(2H)-ylidene)furan-2-carbohydrazides. The anti-inflammatory activity obtained compounds studied. have prono...

In the title mol-ecule, C(23)H(18)FN(3)O(2), the mean plane of the indole system forms dihedral angles of 44.23 (8) and 14.54 (7)°, respectively, with the phenyl and benzene rings. In the crystal, inter-molecular N-H⋯O hydrogen bonds link mol-ecules into two-layer ribbons extended along the b axis. The crystal packing also exhibits weak inter-molecular C-H⋯O, C-H⋯F and C-H⋯π inter-actions.

In the title compound, C24H26FN3O, the cyclo-hexane ring adopts a chair conformation; the propyl substituent is in an equatorial orientation and the bond-angle sum at the C atom bonded to the carbohydrazide N atom is 360.0°. The dihedral angle between the 1H-indole ring system and the phenyl ring is 82.77 (13)°. A weak intra-molecular C-H⋯π contact occurs. In the crystal, pairs of mol-ecules re...

The title compound, C22H22FN3O, crystallized with two independent mol-ecules (A and B) in the asymmetric unit; these are linked by a pair of N-H⋯O hydrogen bonds, forming a pseudo-centrosymmetric dimer with an R (2) 2(10) motif. In addition, a number of C-H⋯π inter-actions are also observed. The 1H-indole ring systems in mol-ecules A and B are essentially planar [maximum deviations of 0.019 (2)...

This research concern with the metal complexes of ligand [N'-{2-(4-isobutyl-phenyl)-propionyl}pyridine-4-carbohydrazide] Co(II), Ni(II) , Cu(II) and Pd(II) have been synthesized characterized by atomic absorption infrared, electronic spectra, molar conductivity magnetic moment measurements. On basis data obtained from above measurements, act as a neutral bidentate octahedral structures are prop...