With the rapid advances in molecular biology, the near completion of the human genome, the development of appropriate statistical genetic methods and the availability of the necessary computing power, the identification of quantitative trait loci has now become a realistic prospect for quantitative geneticists. We briefly describe the theoretical biometrical foundations underlying quantitative ...

In this paper we discuss the complex problem of relating genotype to phenotype and challenge the simple mapping of genes to higher-level cognitive modules. We examine various methods that have been used to investigate this relation, including quantitative genetics, molecular genetics, animal models, and in-depth psychological and computational studies of developmental disorders. Both single gen...

Significant problems in the methods and interpretation of classical quantitative genetics have not been widely recognized or resolved. The problems arise from four fundamental gaps: "Genetic" and "environmental" fractions of variation in traits are distinct from measurable genetic and environmental entities or factors underlying the traits’ development; Standard formulas for partitioning variat...

Researchers in many fields have considered the meaning of two results about genetic variation for concepts of "race." First, at most genetic loci, apportionments of human genetic diversity find that worldwide populations are genetically similar. Second, when multiple genetic loci are examined, it is possible to distinguish people with ancestry from different geographical regions. These two resu...

Over the past 30 years, the characteristics that have made the nematode Caenorhabditis elegans one of the premier animal model systems have also allowed it to emerge as a powerful model system for determining the genetic basis of quantitative traits, particularly for the identification of naturally segregating and/or lab-adapted alleles with large phenotypic effects. To better understand the ge...

Clearly spurred on by Waddington, Bateman (1959) continued the work on the crossveinless phenocopy in Drosophila melanogaster and helped to establish it as a model system in quantitative genetics for threshold traits. In this commentary, I will discuss the context of this work examining the genetic architecture of the crossveinless phenocopy both within the light of current studies of evolution...

[Correction Notice: An Erratum for this article was reported in Vol 16(1) of Emotion (see record 2015-57029-001). In the article, the name of author Joshua M. Tybur was misspelled as Joshua M. Tyber. All versions of this article have been corrected.] Response sensitivity to common disgust elicitors varies considerably among individuals. The sources of these individual differences are largely un...

Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...