نتایج جستجو برای: quinoline derivatives
تعداد نتایج: 107690 فیلتر نتایج به سال:
Neocryptolepine, which is a kind of tetracyclic indoloquinoline alkaloid, exhibits the inhibition of topoisomerase II and shows antiproliferative activity. The present study describes the synthesis and antiproliferative evaluation of several neocryptolepine analogues carrying a branched, functionalized dibasic side chain at C11. These 2-substituted 5-methyl-indolo[2,3-b]quinoline derivatives we...
A new series of 20 quinoline derivatives possessing triazolo, ureido and thioureido substituents have been synthesized and their antimycobacterial properties have been evaluated. Compounds 10, 22 and 24 inhibited Mycobacterium tuberculosis H37Rv up to 96%, 98% and 94% respectively, at a fixed concentration of 6.25 microg/mL. Minimum inhibitory concentration of 3.125 microg/mL was obtained for c...
A simple and efficient method for the synthesis of quinolines and polycyclic quinolines using Li+ modified nanoporous Na+-montmorillonite is described. This new nanocatalyst proceeds via Friedlander annulation under solvent-free conditions. It describes our observations about a trend of catalytic activity of Lithium cation in nanoporous Na+-montmorillonite. In this study, several types of 1,3-d...
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