Asthma management has changed so much in the last 25 years since I began my training pulmonary medicine and set out to be an “asthmatologist.” Back then, all we had were scheduled inhaled corticosteroids (ICSs) bronchodilators, primarily albuterol as a short-acting therapy 4 times per day. Patients often told take 12 puffs (!) of triamcinolone twice daily address inflammation, if things got bad...

Plants have been an important source of medicine for thousands of years. One of the ancient medicinal plant is aloevera. It has been described as a portable Nature’s first aid kit that is an effective, inexpensive first-aid solution for all minor burns and scalds. Aloevera is known for its many health benefits. Over the past decade, interest in drugs derived from medicinal plants has markedly i...

Abstract At a time when the US federal government failed to act on climate change, California's success as subnational policy leader has been widely celebrated. However, landmark law drove wedge between two segments of state's environmental community. On one side was coalition “market-oriented” social movement organizations (SMOs), who allied with private corporations advance market-friendly po...

•Continuously tunable epitaxial strain is achieved beyond substrate limitations•Continuous O-R-T phase transition in BiFeO3 has been obtained on a single substrate•An R/T morphotropic boundary designed SrTiO3 and NdScO3 substrates Epitaxial strain, imparted by an underlying substrate, powerful pathway to drive transitions alter properties complex oxides, enabling the creation of new ground stat...

•Langebaanweg’s (LBW) sabertooth cat’s guild includes two new species•Dinofelis from LBW is the potential ancestor of Plio-Pleistocene Dinofelis•We confirm a Pan-African distribution Adeilosmilus and Lokotunjailurus•Comparison with Eurasian felid implies open environment at Here, we describe revise craniodental material Langebaanweg ‘E’ Quarry (South Africa, early Pliocene, ∼5.2 Ma), which repr...

Indigenous tribes of the interior Columbia River have developed a mutual relationship with native fishes since time immemorial. However, extensive disruption to natural ecosystem has occurred as European settlement North America extended westward utilize abundant resources in ways that conflicted millennia indigenous protection. This anthropogenic disturbance led dramatic declines fish species ...

1 Functional respiratory imaging to assess the interaction between systemic roflumilast and inhaled ICS/LABA/LAMA Vos W, Hajian B, De Backer J, et al. Int J Chron Obstruct Pulmon Dis. 2016;11(1):263-271. doi: http://dx.doi. org/10.2147/COPD.S93830 BACKGROUND: Patients with COPD show a significant reduction of the lobar hyperinflation at the functional residual capacity level in the patients who...

Carrier dynamics in graphene films on CaF2 have been measured in the mid infrared region by femtosecond pump-probe spectroscopy. The relaxation kinetics shows two decay times. The fast time component is ~0.2 ps, which is attributed to the mixture of initial few ultrafast intraband and interband decay channels. The slow component is ~1.5 ps, which is primarily assigned to optical phonon-acoustic...

Results from four studies show that the reliance on affect as a heuristic of judgment and decision making is more pronounced under a promotion focus than under a prevention focus. Two different manifestations of this phenomenon were observed. Studies 1–3 show that different types of affective inputs are weighted more heavily under promotion than under prevention in person-impression formation, ...

Carbon taxes are frequently advocated as a means of reducing greenhouse gas (GHG) emissions, yet their political feasibility remains challenge. To enhance appeal, carbon tax proponents have proposed revenue recycling alleviating public concern with this instrument's visible costs. Analyzing data from identical survey-experiments administered in the United States, Canada, and Germany, we examine...