sarcoplasmic reticulum release. Conversely, 70% Rad knockdown by RNA interference increased ICa (50%), [Ca ]i transients (52%) and contractility (58%) without altering EC coupling efficiency; and the dominant negative mutant RadS105N exerted a similar effect on ICa. Rad upregulation caused depolarizing shift of LCC activation and hastened time-dependent LCC inactivation; Rad downregulation, how...

let $alpha$ be an endomorphism and $delta$ an $alpha$-derivationof a ring $r$.  in this paper we  study the relationship between an$r$-module $m_r$ and the  general polynomial module  $m[x]$ over theskew polynomial ring $r[x;alpha,delta]$. we introduce the notionsof skew-armendariz modules and skew quasi-armendariz modules whichare generalizations of $alpha$-armendariz modules and extend thecla...

The pulse CO-oximeter (Rad-57 Masimo Corporation, Irvine, CA) allows non-invasive and instantaneous measurement of carboxyhemoglobin (COHb) and methemoglobin (MetHb) percentage level using a finger probe. However, the accuracy and reliability of the Rad-57 against the gold standard of venous or arterial blood samples have not been clearly established. Thus, the objective of this trial is to eva...

Activation of D4 receptors (D4Rs) has been shown to improve cognitive performance, potentially affecting synaptic strength. We investigated the D4R agonist PD 168077 (PD) in hippocampal CA1 of freely moving mice. We electrically stimulated in stratum oriens (OR) or radiatum (RAD) and evoked local field potentials (LFPs). Intraperitoneally injected PD dose-dependently and reversibly attenuated L...

The purpose of this paper is to introduce some new classes of rings and modules that are closely related to the classes of almost Dedekind domains and almost Dedekind modules. We introduce the concepts of $\phi$-almost Dedekind rings and $\Phi$-almost Dedekind modules and study some properties of this classes. In this paper we get some equivalent conditions for $\phi$-almost Dedekind rings and ...

PURPOSE To evaluate the combined role of mescenchymal stem cells (MSCs) infected with recombinant adenoviruses expressing human BDNF (rAd/hBDNF) on the erectile dysfunction in rat with cavernous nerve injury. MATERIALS AND METHODS Rats divided into 4 groups: control group, bilateral cavernous nerve crushing group (BCNC group), BCNC with MSCs group and BCNC with MSCs infected with rAd/hBDNF gr...

Let R be a commutative Noetherian ring. The k-torsionless modules are defined in [7] as a generalization of torsionless and reflexive modules, i.e., torsionless modules are 1-torsionless and reflexive modules are 2-torsionless. Some properties of torsionless, reflexive, and k-torsionless modules are investigated in this paper. It is proved that if M is an R-module such that G-dimR(M)

Catlin et al. [1, Corollary 9A] characterised the graphs G with the property that ham(G) > rad(G) + 1 where ham(G) and rad(G) stand for the hamiltonian index and the radius of G, respectively. Here a slightly stronger result is presented. In effect, the graphs for which ham(G) > rad(G) holds are characterised in a similar way.

As a systems development approach, RAD has both critics and supporters whose opinions have led to considerable debate about its application for large, complex information systems (IS) development. Literature supports the view that RAD is not suitable for all types of project but that is generally associated with small/medium projects that have low levels of complexity. Contrary to these publish...

p53 tumor suppressor gene therapy has been proposed for cancers characterized by inactivation of p53 function, and successful therapy will require efficient strategies for gene delivery. To maximize transgene expression in tumors, a clinical strategy has been proposed to treat neoplasms in the liver via hepatic artery administration of a recombinant adenovirus encoding wild-type p53 (rAd-p53). ...