In rats, removal of the carotid arterial or abdominal aortic endothelium results in an acute increase of diameter and compliance. In humans, acute local administration of a specific NO synthase inhibitor increases radial artery compliance but not the diameter. The purpose of this review is to determine whether in spontaneously hypertensive rats (SHR), a cause-and-effect relationship may be obse...

Arterial stiffness and compliance are major predictors of adverse cardiovascular events and are influenced by female sex hormones, including estrogen and progesterone. The aim of this longitudinal study was to evaluate the effect of the menstrual cycle, normal pregnancy, and preeclampsia on central and systemic arterial stiffness. Ten healthy nulliparous women with regular menses were studied i...

BACKGROUND Recent evidence suggests that both the HIV virus and antiretroviral therapy (ART) are associated with premature atherosclerosis in adults. Increased arterial stiffness as assessed by pulse wave velocity (PWV) has been associated with adverse cardiovascular outcome in adults. The relationship between HIV infection and treatment and arterial stiffness has not been evaluated in children...

Strong fibers can fail at low stresses under cyclic loading. This phenomenon, which is called cyclic fatigue, occurs to an unexplained extent only when part (or all) of the fiber is compressed or twisted for some fraction of the strain cycle. Industrial yarns used in rubber, a 2 MMM lb. annual market in which USA fiber producers are highly competitive, must retain a maximum fraction of their in...

Geocell structures consist of a series of interconnected single cells, made from different polymer materials. The cell walls completely encase the infill material and provide an all-around confinement to the soil. The confinement effect is based on three main mechanisms: active earth pressure within loaded cell, passive earth resistance in the adjacent cells and hoop stresses in the cell walls....

The recently proposed concept of spring back reflectors has revolutionised the field of deployable antenna structures. The whole structure is made as a single piece from composite material, without any expensive and potentially unreliable joints, and it is simply folded elastically about a central axis, like a taco shell. Shape distortions occur during manufacturing and are difficult to correct...

A new methodology for determining the radial elastic modulus of a one-dimensional nanostructure laid on a substrate has been developed. The methodology consists of the combination of contact resonance atomic force microscopy (AFM) with finite element analysis, and we illustrate it for the case of faceted AlN nanotubes with triangular cross-sections. By making precision measurements of the reson...

Introduction. Flow-mediated dilation (FMD), low flow-mediated constriction (L-FMC), and reactive hyperemia-related changes in carotid-to-radial pulse wave velocity (ΔPWVcr%) could offer complementary information about both "recruitability" and "resting" endothelial function (EF). Carotid-to-femoral pulse wave velocity (PWVcf) and pulse wave analysis-derived parameters (i.e., AIx@75) are the gol...

Coherent angular rotation of epithelial cells is thought to contribute to many vital physiological processes including tissue morphogenesis and glandular formation. However, factors regulating this motion, and the implications of this motion if perturbed, remain incompletely understood. In the current study, we address these questions using a cell-center based model in which cells are polarized...