The in vitro antioxidant activities of eight 3-carboxycoumarin derivatives were assayed by the quantitative 1,1-diphenyl-2-picrylhydrazil (DPPH•) radical scavenging activity method. 3-Acetyl-6-hydroxy-2H-1-benzopyran-2-one (C1) and ethyl 6-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylate (C2) presented the best radical-scavenging activity. A quantitative structure-activity relationship (QSAR) study ...

Antioxidants play an important role in inhibiting and scavenging radicals, thus providing protection to humans against infections and degenerative diseases. The present article focuses on the synthesis and antioxidant activity studies of a variety of 2-aryl thiazolidine -4-carboxylic acids. A series of twenty fully characterized 2-aryl thiazolidine-4-carboxylic acids have been synthesized by nu...

In the present study, seven hydroxamic acid derivatives of nonsteroidal anti-inflammatory drugs (NSAIDs) (ibuprofen, fenoprofen, ketoprofen, indomethacin and diclofenac) were found to possess significant antioxidant, radical scavenging and metal chelating activities. The most active antioxidant and radical scavenger was N-methylhydroxamic acid of diclofenac (ANT = 88.0% and EC50 = 60.1 microg m...

Moutan cortex, a widely used traditional Chinese medicine for the treatment of various diseases, is the root bark of Peaonia suffruticosa Andrews (Paeoniaceae). In this study, the crude polysaccharides (CPS), paeonol and the crude total glycosides (CTG) of moutan cortex were extracted by the multiple-stage extraction. CPS was extracted by water, paeonol was distilled by steam distillation metho...

this paper is the first phytochemical and abts cation radical decolorisation activity, cupric reducing antioxidant capacity, anticholinesterase and dna damage protection effect of endemic verbascum pinetorum (boiss.) o. kuntze. phenolic profile of v. pinetorum were qualified and quantified by uhplc-esi-ms/ms analysis. malic acid (47250.61±2504.28 µg/g) and luteolin (7651.96±527.98 µg/g) were fo...

Ten phenolic compounds were isolated from a butanol fraction of sage extracts. Their structures were determined by spectral methods (NMR, MS, IR). Among them, a novel compound, 4-hydroxyacetophenone-4-O-â-D-apiofuranosyl-(1f6)-O-â-D-glucopyranoside, was identified. Two test systems, DPPH free radical scavenging activity and radical cation ABTS•+ scavenging activity, were used to evaluate their ...

Four seaweed polysaccharides were extracted from Sarcodia ceylonensis, Ulva lactuca L., Gracilaria lemaneiformis, and Durvillaea antarctica, respectively, by microwave-assisted extraction. The effect of three significant variables (extraction time, extraction temperature, and the ratio of water to raw material) on the process for extracting polysaccharides was investigated, along with the optim...

BACKGROUND Callistemon citrinus (Curtis.) (Family- Myrtaceae) is a popular evergreen shrub in Bangladesh. In the present study, the leaves of this plant have been assessed comprehensively for free radical scavenging, thrombolytic and membrane stabilizing activities. METHODS The leaves were collected, powdered and extracted with methanol. The extract was then concentrated and successively frac...

In this study, water extract of nettle (Urtica dioica L.) (WEN) was studied for antioxidant, antimicrobial, antiulcer and analgesic properties. The antioxidant properties of WEN were evaluated using different antioxidant tests, including reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. WEN had powerful an...

Apitherapy has become the focus of attention as a form of folk and preventive medicine for treating certain conditions and diseases as well as promoting overall health and well-being. In apitherapy, honey is the therapeutic agent used for dressing surgical wounds, burns or skin ulcers, as well as for dyspepsia, peptic ulcer, etc., because of its antioxidant activity. Therefore, it is important ...