Objective: RapidArc (Varian Medical Systems, Palo Alto, CA) is a new volumetric-modulated arc radiotherapy technique with continuous modulation of gantry speed, dose rate, and multileaf collimator shape. Taking advantages of dose painting capabilities along with rotational delivery, RapidArc has shown promise in the treatment of a wide range of tumours, including intracranial, head and neck, pr...

BACKGROUND This study aimed to investigate the tolerability and impact of milk of magnesia (MoM) on interfraction rectal filling during prostate cancer radiotherapy. METHODS Two groups were retrospectively identified, each consisting of 40 patients with prostate cancer treated with radiotherapy to prostate+/-seminal vesicles, with daily image-guidance in 78Gy/39fractions/8 weeks. The first-gr...

BACKGROUND The choice of any radiotherapy treatment plan is usually made after the evaluation of a few preliminary isodose distributions obtained from different beam configurations. Despite considerable advances in planning techniques, such final decision remains a challenging task that would greatly benefit from efficient and reliable assessment tools. METHODS For any dosimetric plan conside...

This discussion paper will explore the impact of using Magnetic Resonance Imaging (MRI) in the treatment of cervical cancer with brachytherapy. It is written from the perspective of current departmental practice in the UK and aims to highlight the issues associated with using MRI as a tool for image guided brachytherapy planning. To support the discussion, a literature review was undertaken foc...

Background: The magnetic resonance imaging (MRI)-based radiotherapy planning method have been considered in recent years because of the advantages of MRI and the problems of planning with two images modality. The first step in MRI-based radiotherapy is to evaluate magnetic resonance (MR) images geometric distortion. Therefore, the present study aimed to evaluate system related geometric distort...

BACKGROUND The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this study was to compare coverage of computed tomography (CT)-based breast and boost planning target volumes (PTV), absolute volumes irradiated, and dose delivered to the organs at ri...

Electrochemotherapy uses electroporation for enhancing chemotherapy. Electrochemotherapy can be performed using standard operating procedures with predefined electrode geometries, or using patient-specific treatment planning to predict electroporation. The latter relies on realistic computer models to provide optimal results (i.e. electric field distribution as well as electrodes' position and ...

A male patient, aged 33, was treated at the Clinic for Oncology, Hematology and Radiotherapy at the University Clinical Center, Tuzla, with the diagnosis of diffuse large B-cell lymphoma. Conformal radiotherapy was conducted on the region of the epipharynx, oropharynx and lymph nodes of the neck on both sides (1). The target volume included the following: the clinical target volume (CTV) of the...

A triple-variable Integral Equation for Tumor Control Cumulative Probability (TCCP) is developed with the addition of important radiotherapy Treatment-Time parameter. Based on a previous double TCCP depending Biological Model parameters (α , β ), NEffective model implemented in (TCP) equation. Results comprise three essential Radiation Therapy precise determination TCCP. Solution shows method t...