This article describes the design and fabrication of a microfluidic mixing system optimized for ultrasensitive optical measurements. Channels are replica-molded in polydimethylsiloxane elastomer and sealed with fused-silica coverglass. The resulting devices have broad chemical compatibility and extremely low fluorescence background, enabling measurements of individual molecules under well-chara...

Related DatabasesWeb of Science You must be logged in with an active subscription to view this.Article DataHistorySubmitted: 14 July 2020Accepted: 30 August 2021Published online: 06 January 2022Keywordsgraph sampling, switch Markov chain, joint degree matrixAMS Subject Headings68Q25, 05C80, 68R10Publication DataISSN (print): 0895-4801ISSN (online): 1095-7146Publisher: Society for Industrial and...