The giomerular mesangium is a supporting structure that includes the mesangial cells and an intercellular substance, the mesangial matrix. Mesangial cells are steilate in shape and resemble morphologically smooth muscle cells (1, 2). They contract in response to binding of angiotensin II (3, 4) and vasopressin (4). They also produce prostaglandins (PG) 1 (5) and synthesize the mesangial matrix ...
