This article describes the R package rdrobust, which provides data-driven graphical and inference procedures for RD designs. The package includes three main functions: rdrobust, rdbwselect and rdplot. The first function (rdrobust) implements conventional local-polynomial RD treatment effect point estimators and confidence intervals, as well as robust bias-corrected confidence intervals, for ave...

The "runt domain" (RD) is a 128 amino acid region of the Drosophila pair-rule gene runt. This highly conserved region delineates the DNA-binding domain of a new family of transcription factors; the RD proteins. The family includes genes from Drosophila, chicken and mammals that are involved in a wide range of developmental processes, from sex determination and neurogenesis in Drosophila to hema...

INTRODUCTION Radiation damping (RD) describes a second-order effect where the signal-induced current in the receiver coil acts back onto the primary spin system [1]. According to Lenz’s law, the RD field acts in a way to oppose its original cause. In that sense RD can be understood as a 1) self-generating and 2) selfregulating flip-back pulse, which causes the transverse magnetization to return...

In the absence of a randomized control trial, regression discontinuity (RD) designs can produce plausible estimates of the treatment effect on an outcome for individuals near a cutoff score. In the standard RD design, individuals with rating scores higher than some exogenously determined cutoff score are assigned to one treatment condition; those with rating scores below the cutoff score are as...

Abstract: Robust design (RD), implemented in statistical and mathematical procedures to simultaneously minimise the process bias and variability, is widely used in many areas of engineering and technology to represent complex real-world industrial settings. For RD modelling and optimisation, response surface methodology (RSM) is often utilised as an estimation method to represent the functional...

The Runt domain (RD) is the DNA-binding region of the Runx genes. A related protein, known as core binding factor beta (CBFbeta) also binds to the RD to enhance RD-DNA interaction by 6- to 10-fold. Here, we report results from molecular dynamics (MD) simulations of RD alone, as a dimer in complexes with DNA and CBFbeta and in a ternary complex with DNA and CBFbeta. Consistent with the experimen...

Mouse mCRY1 and zebrafish zCRY1a and zCRY3 belong to the DNA photolyase/Cryptochrome family. mCRY1 and zCRY1a repress CLOCK:BMAL1-mediated transcription, whereas zCRY3 does not. Reciprocal chimeras between zCRY1a and zCRY3 were generated to determine the zCRY1a regions responsible for nuclear translocation, interaction with the CLOCK:BMAL1 heterodimer, and repression of CLOCK:BMAL1-mediated tra...

OBJECTIVES The primary objective was to investigate the effects of continuous typing on median nerve changes at the carpal tunnel region at two different keyboard slopes (0° and 20°). The secondary objective was to investigate the differences in wrist kinematics and the changes in wrist anthropometric measurements when typing at the two different keyboard slopes. METHODS Fifteen healthy right...

Fast 10 Finger Typing is a blind typing method which means we only value what are going to type and use our instincts without looking at the keyboard. This technique used optimize function of fingers eyes do not get tired easily because they focus on typed writing. has an arrangement placing so that all can in typing. finger exercise will apply fast method, namely by using master method.This se...

Neuroscience has advanced our understanding of the neurological basis of reading disability (RD). Yet, no functional imaging work has been reported on the twice-exceptional dyslexic: individuals exhibiting both non-verbal-giftedness and RD. We compared groups of reading-disabled (RD), non-verbally-gifted (G), non-verbally-gifted-RD (GRD), and control (C) adults on validated word-rhyming and spa...