T-cell/histiocyte-rich diffuse large B-cell lymphoma is characterized by abundant reactive T-cell and histiocyte infiltration within nodal diffuse large B-cell lymphoma, and only limited cases of primary cutaneous T-cell-rich B-cell lymphoma have been documented. These reactive T-cells usually show a T-helper phenotype. Gamma/delta T-cell is a functionally distinct T-cell lineage, which constit...

Circulating human CD4(+)CD25(++)CD127(-)FOXP3(+) T cells with a persistent demethylated regulatory T cell (Treg)-specific demethylated region Foxp3 gene are considered natural Tregs (nTregs). We have shown that it is possible to identify functional Ag-reactive nTregs cells for a range of different common viral and vaccination Ags. The frequency of these Ag-reactive nTregs within the nTreg popul...

In the present study, the biobleaching potential of white rot fungus Cordyceps militaris MTCC3936 was investigated. For preliminary screening, decolorization properties of C. militaris were comparatively studied using whole cells in agar-based and liquid culture systems. Preliminary investigation in liquid culture systems revealed 100% decolorization achieved within 3 days of incubation for rea...

Cutaneous pseudolymphoma (PL) refers to a reactive T or B- cell proliferative disorder in reaction to some known or unknown stimuli. The most common site of involvement of pseudolymphoma is the face followed by the scalp. Because of its similarity with true lymphoma in both clinical and pathological aspects, differentiating between them is often difficult but fundamental due to their completely...

OBJECTIVE The aim of this study was to assess the frequency of mycobacteria and Escherichia coli reactive T cells in intestinal biopsies from patients with Crohn's disease (CD) and ulcerative colitis (UC). MATERIALS AND METHODS The biopsies were obtained by colonoscopy from adult patients with active CD (n = 5) and active UC (n = 4). The number of CD4+ T cell clones expanded and screened from...

objective: oxidative stress plays a key role in the pathophysiology of brain ischemia and neurodegenerative disorders.previous studies indicated that viola tricolor and viola odorataare rich sources of antioxidants. this study aimed to determine whether these plants protect neurons against serum/glucose deprivation (sgd)-induced cell death in an in vitro model of ischemia and neurodegeneration....

the protective effects of rheum tanguticum polysaccharide 1 (rtp1), which is extracted from the chinese traditional medicine rheum tanguticum, on radiation-induced intestinal mucosal injury was investigated. rat intestinal crypt epithelial cells (iec-6 cells) and sprague-dawley rats were each divided into control, irradiated and rtp1-pretreated irradiated groups. after irradiation, cell surviva...

in this study the role of glutathione (gsh) in sulfur mustard -induced oxidative stress and cytotoxicity, in human skin fibroblast cell line (hf2ff) was evaluated. sulfur mustard-induced superoxide radical and hydrogen peroxide formation were evaluated by determination of superoxide dismutase and catalase activity in cell lysate. the cytotoxicity of sulfur mustard was estimated by lactate dehyd...

abstract gastrointestinal mesenchymal tumors are a group of tumors originating from the mesenchymal stem cells of the gi tract. digestive tract schwannomas are rare mesenchymal tumors which occur most frequently in the stomach. we report a 56-yearold woman who was examined endoscopically for dyspepsia which she had suffered from since 3 years ago. around gastric antral mass was seen. surgical r...

purpose: to determine the prevalence of human t-cell lymphotropic virus (htlv) in corneal donors at the eye bank of i.r. iran from 2005 to 2007. methods: serologic tests for htlv-1,2 were performed in all donors at the eye bank from august 2005 to july 2007. hospital and medicolegal reports of htlv-reactive cases as well as their geographic origin were reviewed. results: overall, 5533 donors in...