the life cycle of the american trypanosome, trypanosoma rangeli, in its invertebrate host, rhodnius prolixus, is completed by invasion into the insect salivary glands. as a prerequisite, there is an initial recognition of the salivary gland receptors for the adhesion/invasion by t rangeli. therefore, the purpose of this study was to investigate the putative receptor molecules on either the sali...

Apelin, a peptide hormone, is an endogenous ligand for G protein-coupled receptor and has been shown to be widely expressed in human animal tissues, such as the central nervous system adipose tissue. Recent studies indicate that apelin/APJ involved regulation of multiple physiological pathological processes, it associated with cardiovascular diseases, metabolic disorders, neurological ischemia-...

OBJECTIVE: Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes. C-Reactive Protein (CRP), an acute phase protein produced by hepatocytes, may be associated with diabetes. This study aimed to compare serum levels of CRP in women with gestational diabetes mellitus (GDM), impaired glucose tolerance test and control subjects. MATERIALS AND METHODS: In this ca...

This scientific commentary refers to ‘Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2’ by Xia et al. (doi:10.1093/brain/awab122).

in  this  study  we  determined  the  frequency,  sensitivity  and  specificity  of  anti  cyclic citrullinated peptides (anti-ccp) igg antibody, total rheumatoid factor (rf-t), and rf isotypes in iranian patients with rheumatoid arthritis (ra) and their association with age, clinical and serological parameters. anti-ccp and rf-t and rf isotypes level were measured in 418 patients and 399 healt...

abstract       background and objectives: diabetes induced oxidative stress plays an important role in pathological damage to the heart and liver by increased production of extracellular matrix. it is thought that the use of medicinal plants, particularly portulaca oleracea. l and regular exercise are effective. the aim of this study was to evaluate the effects of portulaca oleracea. l consumpt...