Immunological heterogeneity has long been the major challenge in developing broadly effective vaccines to protect humans and animals against bacterial and viral infections. Enterotoxigenic Escherichia coli (ETEC) strains, the leading bacterial cause of diarrhea in humans, express at least 23 immunologically different colonization factor antigens (CFAs) and two distinct enterotoxins [heat-labile...

OBJECTIVES Evaluation of the LightMix® modular carbapenemase kits for the rapid detection of carbapenemase-producing Enterobacteriaceae (CPE) and the application of these kits to the direct detection of colonized patients and bacteraemias. METHODS The modular multiplex PCR kits targeting blaKPC, blaNDM, blaVIM, blaIMP and blaOXA-48-like carbapenem resistance genes were evaluated in terms of s...

BACKGROUND A CTX-M-15 extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae was responsible for an outbreak in the neonatal intensive care unit (NICU) at Stavanger University Hospital, Norway over a 5-month period (November 2008-April 2009). The risk factors for acquiring ESBL-producing K. pneumoniae during the outbreak were examined in this study. METHODS Faecal or rectal c...

1 Department of Infectious Diseases, Faculty of Medicine, Erciyes University, Kayseri, Turkey 2 Department of Clinical Microbiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey 3 Infection Control Committee, Faculty of Medicine, Erciyes University, Kayseri, Turkey 4 Department of Public Health, Faculty of Medicine, Erciyes University, Kayseri, Turkey 5 Department of Pediatrics, Fac...

  Rectal cancer is the second most common cancer in large intestine. The prevalence and the number of young patients diagnosed with rectal cancer have made it as one of the major health problems in the world. With regard to the improved access to and use of modern screening tools, a number of new cases are diagnosed each year. Considering the location of the rectum and its adjacent organs, ma...

Lactobacilli colonizing the rectum may be a reservoir for vaginal lactobacilli. In a cross-sectional study of 531 females, vaginal and rectal colonization by lactobacilli were assessed by culture methods. A subset of isolates was identified to the species level by use of whole-chromosomal DNA probes. Lactobacillus crispatus (16%), L. jensenii (10%), and L. gasseri (10%) were the prevalent lacto...

In bacteria, Hfq is a core RNA chaperone that catalyzes the interaction of mRNAs with regulatory small RNAs (sRNAs). To determine in vivo RNA sequence requirements for Hfq interactions, and to study riboregulation in a bacterial pathogen, Hfq was UV crosslinked to RNAs in enterohemorrhagic Escherichia coli (EHEC). Hfq bound repeated trinucleotide motifs of A-R-N (A-A/G-any nucleotide) often ass...

the effect of intracerebroventricular injections of prostaglandins e2 and f2a was studied on the rectal temperature of sheep. pge2 but not pgf2a at the same dose of 50mg elevated the 1h post-injection of rectal temperature. pge2 but not pgf2a at the same dose of 100mg increased 3.5 and 2h post-injection of rectal temperature, respectively. elavation of rectal temperature following pge2 and pgf2...

rectal prolapse is a relatively common disease of children and is defined as a rectal mucosa protrusion or a fullthickness protrusion (all layers) from anus. the purpose of this retrospective study is the review of different surgical techniques used in our centers and recommendations for optimal surgical management of rectal prolapse. this study was based on a 19 years experience in rectal prol...

BACKGROUND AND OBJECTIVE Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important enteric pathogen in human causing bloody or nonbloody diarrhea, which may be complicated by hemolytic uremic syndrome (HUS). Cattle are an important reservoir of EHEC. This research aims at vaccination with a divalent chimer protein composed of EspA120 and Intimin 282 and its preventive effect of EHEC O15...