BACKGROUND The aim was to evaluate the applicability of laparoscopic surgery in the treatment of primary rectal cancer in a training unit. METHODS A cohort analysis was undertaken of consecutive patients undergoing elective surgery for primary rectal cancer over a 7-year interval. Data on patient and operative details, and short-term clinicopathological outcomes were collected prospectively a...

This clinical practice guideline represents a collaborative effort between the American Society of Colon and Rectal Surgeons (ASCRS) and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). The ASCRS Clinical Practice Guidelines Committee is composed of society members who are chosen because they have demonstrated expertise in the specialty of colon and rectal surgery. In a...

PURPOSE The impact of weight loss on obesity-related colorectal cancer (CRC) risk is not well defined. Previous studies have suggested that Roux-en-Y gastric bypass (RYGB) surgery may have an unexpected adverse impact on CRC risk. This study aimed to investigate the impact of RYGB on biomarkers of CRC risk. MATERIALS AND METHODS Rectal mucosal biopsies and blood were obtained from patients un...

As cancer care becomes increasingly complex and multidisciplinary, the availability of timely and complete clinical information is critical to decisionmaking. Complete clinical information is particularly relevant in the care of stages i–iii rectal cancer: surgery, radiotherapy, and chemotherapy all play a major role, and the selection of such therapies is of utmost importance. Surgery for nonm...

BACKGROUND Adequate lymph nodes resection in rectal cancer is important for staging and local control. This retrospective analysis single center study evaluated the effect of neoadjuvant chemoradiation on the number of lymph nodes in rectal carcinoma, considering some clinicopathological parameters. METHODS A total of 111 patients undergone total mesorectal excision for rectal adenocarcinoma ...

There are several surgical techniques for the treatment of hemorrhoidal disease, most used currently being stapled hemorrhoidopexy. Complications this procedure rare, although they may occur. The aim study is to report clinical case a patient with severe complication rectal perforation after A 44-year-old man who presented anal pain in his postoperative period hemorrhoid urgent computed tomogra...

INTRODUCTION The abdominal approach for the treatment of rectal tumours is associated with considerable morbidity. Transanal endoscopic microsurgery (TEM) is a technical alternative, and less invasive than radical surgery, and thus, with a lower associated morbidity. Also, with the correct selection of patients, TEM shows similar oncological results to radical surgery. The objective of this stu...

PURPOSE Neoadjuvant therapy is able to reduce local recurrence in rectal cancer. Immediate surgery after short course radiotherapy allows only for minimal downstaging. We investigated the effect of delayed surgery after short-course radiotherapy at different time intervals before surgery, in patients affected by rectal cancer. METHODS From January 2003 to December 2013 sixty-seven patients wi...

Livin is a novel member of the inhibitor of apoptosis protein family, which has been identified to be expressed in various malignancies and is suggested to be associated with poor prognostic significance. However, no data are available concerning the significance of livin in mid-distal rectal cancer. In the present study, livin expression, and its association with clinicopathological characteri...