OBJECTIVE To evaluate cognitive outcome in adult survivors of bacterial meningitis. METHODS Data from three prospective multicentre studies were pooled and reanalysed, involving 155 adults surviving bacterial meningitis (79 after pneumococcal and 76 after meningococcal meningitis) and 72 healthy controls. RESULTS Cognitive impairment was found in 32% of patients and this proportion was simi...

Bacterial meningitis is the most common and serious bacterial infection of the central nervous system (CNS), characterized by an acute purulent infection of the piamater, arachnoid and subarachnoid space1. Approximately 1.2 million cases are estimated to occur annually world-wide, resulting in 135,000 deaths2,3. Streptococcus pneumoniae and Neisseria meningitidis are the main etiologic agents r...

Background and Aims: Identifying meningitis-causing bacteria play an important role in selecting the appropriate antibiotic vaccine and reducing the complications of meningitis. The present study aimed to identify the most common bacteria causing meningitis in patients referred to Afzalipour Hospital in Kerman. Materials and Methods: In this cross-sectional study, 60 patients have participated...

We describe a case of persistent strongyloidiasis complicated by recurrent meningitis, in a human T cell lymphotropic virus type 1 (HTLV-1) seropositive Peruvian migrant adult resettled in Italy. He was admitted with signs and symptoms of acute bacterial meningitis, reporting four other meningitis episodes in the past 6 years, with an etiological diagnosis of Escherichia coli and Enterococcus f...

Bacterial meningitis causes persisting neurofunctional sequelae. Theoccurrence of apoptotic cell death in the hippocampal subgranular zone of the dentate gyrus characterizes the disease in patients and relates to deficits in learning and memory in corresponding experimental models. Here, we investigated why neurogenesis fails to regenerate the damage in the hippocampus associated with the persi...