نتایج جستجو برای: redox homeostasis

تعداد نتایج: 112752  

Journal: :Antioxidants & redox signaling 2014
Ana I Rojo Gethin McBean Marina Cindric Javier Egea Manuela G López Patricia Rada Neven Zarkovic Antonio Cuadrado

Neurodegenerative diseases are characterized by chronic microglial over-activation and oxidative stress. It is now beginning to be recognized that reactive oxygen species (ROS) produced by either microglia or the surrounding environment not only impact neurons but also modulate microglial activity. In this review, we first analyze the hallmarks of pro-inflammatory and anti-inflammatory phenotyp...

2016
Zsuzsanna Géhl Edina Bakondi Miklós D. Resch Csaba Hegedűs Katalin Kovács Petra Lakatos Antal Szabó Zoltán Nagy László Virág

PURPOSE Diabetes is accompanied by fundamental rearrangements in redox homeostasis. Hyperglycemia triggers the production of reactive oxygen and nitrogen species which contributes to tissue damage in various target organs. Proliferative diabetic retinopathy (PDR) is a common manifestation of diabetic complications but information on the possible role of reactive intermediates in this condition ...

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