A simple and efficient method for the synthesis of 1,1-diarylalkanes via the Friedel-Crafts-type alkylation reaction of electron-rich arenes with cinnamic acid ester derivatives or chalcones is reported. Iron triflate has been found to be the best catalyst for the Friedel-Crafts-type alkylation reaction with α,β-unsaturated carbonyl compounds. This reaction afforded β,β-diaryl carbonyl compound...

Key Points Fire  Elemental nickel dust and nickel carbonyl are flammable  Nickel is incompatible with acids, oxidizing agents and sulphur  Nickel and nickel carbonyl react violently with oxidants  Nickel and nickel compounds emit toxic fumes and vapours of nickel carbonyl when heated to decomposition  In the event of a fire involving nickel carbonyl, use fine water spray and gas tight kit ...

Mixture of the trimethylchlorosilane, magnesium and hexamethylphosphorictriamid, HMPT, react with epoxyketones to produce tetrasiliciated compounds, which are the results of the addition of two trimethylsilyl (TMS) groups to the carbonyl function and two TMS groups to the expoxide cycle. After elimination of (Me Si) O siliciated enoxysilanes are obtained which under acidic conditions gives ...

β-cyclodextrin sulfuric acid as a green lewis acid catalyst has been applied for the preparation of bis(indolyl)methanes, tris(indolyl)methanes and 3,3'-diindolyloxindole derivatives by the condensation of indoles with various carbonyl compounds in aqueous media with high to excellent yields.

The first exclusive regioselective fragmentation of primary ozonides controlled by remote carbonyl groups on ozonolysis of norbornene derivatives and reaction of final ozonides with triethylamine as a new probe for determining the regiochemistry of carbonyl oxide formation from primary ozonide fragmentation are reported. Ozonolysis of the endo adducts 3a-d and the deuterated compounds 8a and 8b...