OBJECTIVES/HYPOTHESIS To determine whether measurement of pepsin in throat sputum by immunoassay could be used as a sensitive and reliable method for detecting laryngopharyngeal reflux (LPR) compared with 24-hour double-probe (esophageal and pharyngeal) pH monitoring. STUDY DESIGN Patients with clinical LPR undergoing pH monitoring provided throat sputum samples during the reflux-testing peri...

PURPOSE The Roux en Y method has rarely been performed due to longer operation time and high risk of complication, despite several merits including prevention of bile reflux. We conducted a retrospective review of the result of Roux en Y reconstruction using two circular staplers after subtotal gastrectomy. MATERIALS AND METHODS From December 2008 to May 2009, a total of 26 patients underwent...

in this present study, volume of fluid method in openfoam open source cfd package will be extended to consider phase change phenomena with modified model due to condensation and boiling processes. this model is suitable for the case in which both unsaturated phase and saturated phase are present and for beginning boiling and condensation process needn't initial interface. both phases (liqu...

BACKGROUND/AIMS Impedance-pH monitoring allows detailed characterization of gastroesophageal reflux and esophageal activity associated with reflux. We assessed the characteristics of nocturnal reflux and esophageal activity preceding and following reflux. METHODS Impedance-pH tracings from 11 healthy subjects and 76 patients with gastroesophageal reflux disease off acid-suppressive therapy we...

BACKGROUND/AIMS Available data about reflux patterns and symptom determinants in the gastroesophageal reflux disease (GERD) subtypes off proton pump inhibitor (PPI) therapy are lacking. We aimed to evaluate reflux patterns and determinants of symptom perception in patients with GERD off PPI therapy by impedance-pH monitoring. METHODS We retrospectively reviewed the impedance-pH data in patien...

A highly simple, rapid, sensitive and selective method is developed for spectrophotometric determination of gabapentin in pure form as well as in pharmaceutical formulations. The method is based on the formation of a yellow Schiff base derived from the condensation of gabapentin drug (1-amino methyl) cyclo hexane acetic acid and 2,5-dihydroxybenzaldehyde (DHBA) exhibiting a maximum absorbance a...

BACKGROUND AND AIM The reason that some reflux episodes evoke symptoms is poorly understood, therefore the aim of this study is to assess the determinants of reflux perception in patients with non-erosive reflux disease (NERD) on proton pump inhibitor (PPI) therapy. METHODS Ten NERD patients with persistent symptoms, despite double-dose PPI therapy, were included in this study. All patients h...

A realistic numerical model is used to study the circulation and mixing of Salish Sea, a large, complex estuarine system on United States Canadian west coast. The Sea biologically productive supports many important fisheries but threatened by recurrent hypoxia ocean acidification, so clear understanding its patterns residence times value. exchange flow quantified at 39 sections over 3 years (20...

Schiff bases are the compounds containing azomethine group (-HC=N-). They formed by condensation of ketones or aldehydes with a primary amine. Formation base generally takes place under acid/base catalysis heat. The common crystalline solids, which basic but at least some form insoluble salts strong acids. used as intermediates for synthesis amino acids ligands preparation metal complexes havin...