The Internet in its current form relies on extensive cooperation between network operators to ensure the integrity and security of its core infrastructure. Here we describe how routing registries can be used to improve the security of the Internet infrastructure in general and the BGP routing protocol in particular. Routing registries can be used to generate accurate prefix filter lists as well...

Pulmonary arterial hypertension (PAH) is a progressive, angio-obliterative disease leading to increased pulmonary vascular resistance, right heart failure, and death in ,25–60% of PAH patients 5 years after diagnosis [1–3]. The estimated prevalence of PAH is 15–50 cases per million adults [4–6] and 2–16 cases per million children [7–9]. In certain at-risk groups, however, the occurrence of PAH ...

In this issue of the journal, Jernberg and colleagues describe the longterm outcomes of the universe of patients admitted between 2006 and 2011 to Swedish hospitals with a diagnosis of acute myocardial infarction. Over a median follow-up of 2.5 years, the study identified relatively higher rates of subsequent cardiac events, almost double thosedescribed in contemporary clinical trials. –5 Using...

in the number of national as well as international registries for a variety of neurological conditions, with corresponding increase in the amount of publications arising from these efforts [ref]. The registries were established for determining the natural history of a specific disease, the effectiveness of new treatments, the quality of care and/or other patient-related outcomes. The purpose of...