We present a category equivalent to that of semi-Nelson algebras. The objects in this are pairs consisting semi-Heyting algebra and one its filters. filters must contain all the dense elements satisfy an additional technical condition. also show case dually hemimorphic algebras, not necessary is

The structure of Medicare and Medicaid creates conflicting incentives regarding dually eligible beneficiaries without coordinating their care. Both Medicare and Medicaid have an interest in limiting their costs, and neither has an incentive to take responsibility for the management or quality of care. Examples of misaligned incentives are Medicare's cost-sharing rules, cost shifting within home...

We describe a cooperad structure on the simplicial bar construction on a reduced operad of based spaces or spectra and, dually, an operad structure on the cobar construction on a cooperad. We also show that if the homology of the original operad (respectively, cooperad) is Koszul, then the homology of the bar (respectively, cobar) construction is the Koszul dual. We use our results to construct...

Information geometry is an important tool to study statistical models. There are some examples in models which regarded as warped products. In this paper, we information of We consider the case where product and its fiber space equipped with dually flat connections and, particular a cone, characterize on base $$\mathbb {R}_{>0}$$ . The resulting turn out be $$\alpha $$ -connections = \pm {1}$$

The transcription factor NFAT1 and the oncogene MDM2 have crucial roles in breast cancer development, progression, and metastasis. We have recently discovered that NFAT1 activates MDM2 expression. Here, we identified a small molecule (named Inulanolide A) that dually inhibited both NFAT1 and MDM2 in breast cancer cells in vitro and in vivo. Unlike conventional MDM2 inhibitors, Inulanolide A (In...

Use of biodiesel as an alternative to non-renewable sources of energy has become an attractive option in recent years. The enzymatic synthesis of biodiesel by transesterification of fats/oils with an alcohol is a much more sustainable route than the chemical method. However, cost effectiveness of the enzymatic route is a major barrier in its commercialization. In this work, a high activity bioc...

A multitude of component models exist today, characterized by slightly different conceptual architectural elements, focusing on a specific operational domain, covering different phases of component life-cycle, or supporting analysis of different quality attributes. When dealing with different variants of products and in evolution of systems, there is a need for transformation of system models f...

The present study explored the behavioral profile of individuals with fragile X syndrome during adolescence and adulthood. Individuals with both fragile X syndrome and autism (n  =  30) were compared with (a) individuals diagnosed with fragile X syndrome (but not autism; n  =  106) and (b) individuals diagnosed with autism (but not fragile X syndrome; n  =  135) on measures of autism symptoms, ...

The present study examined substance refusal skills of 44 conduct-disordered male adolescents. Fifty percent of these adolescents were dually diagnosed with substance abuse/dependence. Substance refusal skills were assessed utilizing a role-play test that consisted of four interpersonal scenarios in which a confederate prompted youths to engage in illicit drug and alcohol activity. The test dem...