Peroxisome Proliferator-Activate Receptors (PPARs) are transcription factors belonging to the nuclear receptor superfamily. The three PPARs (alpha, beta/delta, and gamma) are distributed differently in the different organs. PPARalpha is most common in the liver, but also found in kidney, gut, skeletal muscle and adipose tissue, while PPARbeta/delta, is fairly ubiquitous; it may be found in body...

BACKGROUND Patients with coronary heart disease often do not follow prescribed physical activity recommendations. The aim of this study was to assess the efficacy of a behavioural intervention to increase physical activity in patients with coronary heart disease not attending structured cardiac rehabilitation programmes. METHODS Parallel randomised controlled trial comparing 6-month multi-com...

BACKGROUND Chronic obstructive pulmonary disease (COPD) is often associated with other chronic diseases. These patients are often admitted to hospital based rehabilitation programmes. OBJECTIVES To determine the prevalence of chronic comorbidities in patients with COPD undergoing pulmonary rehabilitation and to assess their influence on outcome. DESIGN Observational retrospective cohort stu...

objective: fragile x syndrome is the second etiology for inherited mental retardation. it may concomitant with other psychiatric disorders. intellectual disability (id) is a state of functioning that typically begins in childhood and is characterized by limitations in intelligence and adaptive skills. we intend to introduce a male young patient with fragile x syndrome and obsessive-compulsive d...

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BACKGROUND Pedometer programs can increase physical activity in sedentary individuals, a population that is at risk for developing metabolic syndrome and each of its individual components. Although the popular 10,000 steps/day recommendation has shown to induce many favorable health benefits, it may be out of reach for sedentary individuals. This study observed the effects of incremental increa...

background: metabolic syndrome (mets) is a serious public health concern worldwide; however, the pathogenesis of this disease has not been yet cleared. this study aimed to compare diet quality in obese/overweight participants with/without metabolic syndrome with normal weight controls.   methods: this was a comparative study on 147 iranian adults under treatment at the endocrinology center of t...

background : the metabolic syndrome has known as an independent risk factor of stroke. the occurrence of this syndrome is due to genetic factors and lifestyle. this study was performed   on the frequency of metabolic syndrome prevalence in ischemic stroke patients compare to control. methods : one hundred ischemic stroke patients and 100 controls (with the same age and sex) were evaluated for t...

background: the correlation of metabolic syndrome and migraine headache was evaluated in some previous studies. however there is no study that compared the prevalence of metabolic syndrome in the patients with and without migraine. control of coincidental factors such as metabolic syndrome reduces therapeutic resistance in migrainous patients. the aim of this study was to compare prevalence of ...