BACKGROUND Renal cell carcinoma accounts for 90% of renal neoplasms and metastatic disease is common. One third of newly diagnosed cases will have synchronous metastases at diagnosis and further 25-50 % will develop metachronous disease. CASE PRESENTATION This study presents two new cases of gallbladder metastasis from renal cell carcinoma (RCC) from our institution and reviews the published ...

INTRODUCTION Laparoscopic port-site metastasis is a rare but well recognized outcome following surgery in urological cancers, with its etiology not clearly understood. Additionally, vaginal metastasis in clear cell renal cell carcinoma is rare, and has not been previously reported in the setting of papillary renal cell carcinoma. CASE PRESENTATION We present the case of a 71-year-old Chinese ...

Cutaneous metastasis develops in 5 to 10 percent of high-stage cancer patients. About 6 percent of cutaneous metastases are caused by renal cell carcinomas (RCC). A 64-year-old man presented with a 4-month history of a rapidly enlarging lesion on the mental region. There was a 2 cm x 3 cm multilobular and polypoid angiomatous tumor in the center of the swelling. Histopathologic examination reve...

PURPOSE To explore the mechanisms underlying clear-cell renal cell carcinoma (ccRCC) metastasis using transcriptional profiling and bioinformatics analysis of ccRCC samples, and to elucidate the role of FOXO3a in ccRCC metastasis. EXPERIMENTAL DESIGN Gene expression profiling was performed using four primary metastatic and five primary nonmetastatic ccRCC samples. The mRNA and protein levels ...

Abstract Prostate cancer is one of the most common cancers affecting men. Bone scan part staging modality commonly used to evaluate bone metastasis. A with diffused increased skeletal tracer uptake relative soft tissue, combined faint renal activity known as a superscan. However, primary concern are false negatives associated scans, where diffuse metastasis indistinguishable on superscans. In t...

Metastasis from urothelial carcinoma to the testis is rare. This case report presented an extremely rare case of testicular metastasis from renal pelvis carcinoma in a 69 year old man who had experienced painless left testicular swelling, after he underwent radical nephroureterectomy and bladder cuff excision for the urothelial carcinoma of left renal pelvis ten years ago. Physical examination ...

The purpose of this study was to determine whether the methods for isolating tumor cells from a human renal cell carcinoma (HRCC) influence the biological behavior of the cancer cells. Renal cell carcinoma obtained from a surgical specimen was dissociated by enzymatic treatment and cells were plated into culture dishes or injected s.c. into the kidney of BALB/c nude mice. The resultant kidney t...

Using a micro-single radial immunodiffusion method, quantitative studies have been made on the serum proteins of 30 renal cancer patients; 15 patients without metastasis and 15 patients with metastasis, and expressed by percentage of those obtained on 98 normal volunteers regarded as 100%. Of 45 proteins studied, 4 (Pre, Alb, alpha 2HS and Tf) significantly decreased and 10 (alpha 1AT, alpha 1A...

Malignant kidney neoplasms are the most frequently encountered solid kidney masses. Although renal cell carcinoma is the major renal malignancy, other solid malignant renal masses should be considered in the differential diagnosis of solid renal masses that do not contain a macroscopic fatty component. In this pictorial essay, we present the imaging findings of a primitive neuroectodermal tumor...

Clear cell renal carcinoma is the most common histological type, representing 70-80% of all renal carcinomas. Metastases are already present in about 25-30% of patients at the time of diagnosis of renal cell carcinoma. Ocular metastasis is extremely rare.