BACKGROUND Cardiovascular disease (CVD) is the leading cause of death after renal transplantation with a high prevalence in dialysis patients. It is still a matter of debate how to assess the cardiovascular risk in kidney transplant candidates. Several approaches and scores exist and found their way into the guidelines. METHODS AND RESULTS We herein assessed PROCAM, Framingham, ESC-SCORE and ...

BACKGROUND Blood transfusions have the potential to improve graft survival, induce sensitization, and transmit infections. Current clinical practice is to minimize transfusions in renal transplantation candidates, but it is unclear if the evidence continues to support pre-transplant transfusion avoidance. Changes in the Medicare prospective payment system may increase transfusion rates. Thus th...

Since Banting and Best’s discovery of insulin in 1921, the administration of exogenous insulin has been the primary treatment for type 1 diabetes. Although this therapy has enabled millions to survive and lead fairly normal lives, it has fallen short of a cure. Type 1 diabetes affects millions of individuals and is associated with multiple medical problems, including renal failure and a reduced...

AIM To explore the benefits and harms of corticosteroid (CS) minimization following renal transplantation. METHODS CS minimization attempts to improve cardiovascular risk factors (hypertension, diabetes, dyslipidemia), to enhance growth in children, to ameliorate bone disease and to lead to better compliance with immunosuppressive agents. Nevertheless, any benefit must be carefully weighed ag...

BACKGROUND Left ventricular assist device (LVAD) and inotrope therapy serve as a bridge to transplant (BTT) or as destination therapy in patients who are not heart transplant candidates. End-stage heart failure patients often have impaired renal function, and renal outcomes after LVAD therapy versus inotrope therapy have not been evaluated. METHODS In this study, 169 patients with continuous ...

BACKGROUND AND OBJECTIVES Although physical function is a major determinant of health outcomes and quality of life in older adults, standard tools for its assessment have not been routinely applied to the fastest growing segment of the kidney transplant candidate population, which is at high risk of comorbidity and disability--people over age 60. The objective of this study was to describe the ...

Abstract Purpose Those of black descent make up 22.7% people in the UK receiving dialysis. A Registry data analysis transplant outcomes on Black-Population (BP) was done and a comparative assessment with Caucasian-Population (CP) renal recipients performed. Methods We harmonized Renal-Transplant Data to shortlist transplants Black Caucasian patients from year 2000-2019. The demographics surviva...

Renal transplant vein stenosis is a rare cause of allograft dysfunction. Percutaneous stenting appears to be safe and effective treatment for this condition. A 56-year-old Caucasian female with end stage renal disease received a deceased donor renal transplant. After transplant, her serum creatinine improved to a nadir of 1.2 mg/dL. During the third posttransplant month, her serum creatinine in...

Background & Aims: Hypertension, hyperuricaemia and nephrotoxicity are some common side-effects of Cyclosporine A (CsA) treatment in renal transplant recipients. Previous studies suggest that Calcium Channel Blockers (CCB) can increase serum level of CsA and may improve graft function in patients receiving CsA. The aim of this study was to evaluate the effects of Diltiazem and Amlodipine on cyc...