The mechanism behind iodinated radiocontrast nephropathy remains elusive. Direct oxidative damage is the prevailing hypothesis, but the apparent protective effect of iodine against oxidation contradicts this view. We propose that autonomic dysfunction participates in the pathogenesis of radiocontrast nephropathy and may account for other contrast-associated reactions previously attributed to al...

BACKGROUND To analyze our experience with renal gunshot wounds (GSW). METHODS We analyzed our prospective trauma database for patients with renal GSW. RESULTS Two hundred one patients (206 renal units) with renal GSW were collected from our database. Preoperative imaging (1-shot intravenous pyelogram, dedicated intravenous pyelogram, or computed tomography) was performed in 68.7% (n = 140)....

Renal biopsies commonly display tissue remodeling with a combination of many different findings. In contrast to trauma, kidney remodeling largely results from intrinsic responses, but why? Distinct danger response programs were positively selected throughout evolution to survive traumatic injuries and to regenerate tissue defects. These are: (1) clotting to avoid major bleeding, (2) immunity to...

BACKGROUND Despite broad clinical use of the American Association of the Surgery of Trauma (AAST) injury scale for kidney, it has only been found to predict the need for renal surgery in single institution series. We sought to validate this scheme for morbidity and mortality in a national cohort of patients with renal injury. METHODS A retrospective cohort design was used to determine the ass...

Complete ureteropelvic junction (UPJ) disruption is a rare finding after blunt abdominal trauma. High clinical suspicion and close attention to imaging studies are needed to avoidmissing a UPJ disruption during initial evaluation. In high grade renal trauma, the best imaging modality to detect collecting system injury and urinary extravasation is computed tomography (CT) scanwith delayed excret...

background: acute kidney injury (aki) is a common problem in critically ill patients and is independently associated with increased morbidity and mortality. recently, serum cystatin c has been shown to be superior to creatinine in early detection of renal function impairment. we compared estimated gfr based on serum cystatin c with estimated gfr based on serum creatinine for early detection of ...

Simple Nephrectomy is a standard therapeutic urological procedure for irreversibly damaged non functioning kidneys involved by different benign pathological conditions like extensive renal stone disease, obstruction due to impacted calculus in the kidney or ureter,trauma,nephrosclerosis,neglected pelviureteric junction obstruction(PUJO),congenital malformations, renovascular hypertension due to...

Abdominal trauma is responsible for most genitourinary injuries. The incidence of renal artery injury and intrathoracic kidney is quite low in patients who present with blunt trauma experiencing damage. There are four defined etiologies for intrathoracic kidney, which include real intrathoracic ectopic kidney, eventration of the diaphragm, congenital diaphragmatic herniation, and traumatic diap...

We report a case of the Page kidney phenomenon which occurred in a patient with a renal allograft following blunt trauma. The injury occurred following an accidental trip resulting in a trivial fall. The patient presented with acute graft dysfunction with no localizing symptoms or signs. His renal function deteriorated further and he also became hypertensive. Serial ultrasounds showed an increa...