نتایج جستجو برای: repeat
تعداد نتایج: 73564 فیلتر نتایج به سال:
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) acquire new spacers to generate adaptive immunity in prokaryotes. During spacer integration, the leader-preceded repeat is always accurately duplicated, leading to speculations of a repeat-length ruler. Here in Haloarcula hispanica, we demonstrate that the accurate duplication of its 30-bp repeat requires two conserved mid-repe...
Myotonic dystrophy (DM) is associated with an underlying CTG trinucleotide repeat expansion at a locus on chromosome 19q13.3. We have determined the repeat length in 23 DM patients with varying clinical severity of symptoms and various sizes of repeat amplification. We confirm that as in previous studies there is no strong correlation between repeat length and clinical symptoms but find that th...
background: the rejected films in radiography may be responsible for an unnecessary increase in the radiation dose to the population. the effective dose to population is a very important factor in estimation of stochastic risk in radiology. the main goal of this study was to determine the effective dose to members of the public due to rejected films in diagnostic radiology departments in the no...
A line of research has revealed that a polymorphism in the promoter region of the MAOA gene is related to antisocial phenotypes. Most of these studies examine the effects of lowMAOA activity alleles (2-repeat and 3-repeat alleles) against the effects of high MAOA activity alleles (3.5-repeat, 4-repeat, and sometimes 5-repeat alleles), with research indicating that the low MAOA activity alleles ...
C9orf72 repeat expansions are a common cause of amyotrophic lateral sclerosis and frontotemporal dementia. To date, no large-scale study of dementia with Lewy bodies (DLB) has been undertaken to assess the role of C9orf72 repeat expansions in the disease. Here, we investigated the prevalence of C9orf72 repeat expansions in a large cohort of DLB cases and identified no pathogenic repeat expansio...
Repeat finding in strings has important applications in subfields such as computational biology. Surprisingly, all prior work on repeat finding did not consider the constraint on the locality of repeats. In this paper, we propose and study the problem of finding longest repetitive substrings covering particular string positions. We propose an O(n) time and space algorithm for finding the longes...
A 28-year-old man presented with abdominal pain and diarrhea (10-12 Bristol type 7 stools per day; Bristol scale range, 1-7 [1, separate hard pieces; 7, watery stool])1 after completing a course of azithromycin for pneumonia. He was diagnosed with Clostridium difficile infection (CDI) with a positive stool polymerase chain reaction (PCR) for the toxin B (tcdB) gene. Laboratory studies showed un...
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