T paper by Kubota et al. in this issue of PNAS (1) describes several significant contributions that bring us much closer to extending ‘‘gene targeting’’ to mammalian species other than the mouse. Gene targeting now provides the means for creating new strains of mice with mutations in virtually any gene. First, the desired mutation is introduced into a cloned copy of the chosen gene by standard ...

An attempt is made to 11;erstand the behaviors involved in two different self-control strategies: Zen meditation and behavioral self-management. The first technique is derived from the Eastern "religious-Philosophical"-tradition of Zen Buddhism; the other technique is derived from laboratory and field studies in Western settings. Using to s of naturalistic observation -and experimental analysis...

In the past tractability issues have generally forced economists to focus their attention on specialized aspects of economic behavior without detailed consideration of psychological cultural demographic and migratory pro cesses The recent development of agent based compu tational frameworks such as the Sugarscape model de veloped by Joshua Epstein and Robert Axtell at the Brookings Institution ...

MF-$0.65 HC-$3.29 Age Differences; classification; *Conservation (Concept); Educational Research; *Elementary school Students; Grade 1; Grade 2; Learning Processes; *Mathematical Concepts; Relationship; *serial Ordering; *Student Testing; Training The purposes of this study were to: (1) determine the influence of a series of experiences involving the equivalence relation "same length as" and th...

Br ain h orm on es exq uisitely r egu late the secr etion of ho rm ones s ecreted by th e p ituitary g lan d that affect gr owth, metabolism , and repr odu ction . Ox ytocin w as on e o f the firs t neur oen docrine hor mo nes is olated and ch aracterized in 1 955 . Cu rr ently, 5 0 neur opeptide ho rmo nes r ang in g f rom mo no amines to p oly peptides w ith > 5,000 mo lecular weigh t have be...

no need to define MUAC if you don't report it in the abstract Response: We agree and removed MUAC from the abstract. The results section of the abstract should specify "symptoms" of zoster and thrush, unless these were more definitive diagnoses? Response: We inserted “symptoms of” as suggested. Methods, second para: do you mean "loss to follow-up" or "non-response"? Response: We mean indeed non...

s International, 59-A, 3662. Risman, B. J. (1987). Intimate relationships from a microstructural perspective: Men who mother. Gender and Society, 1, 6 – 32. *Rivers, I., Poteat, V. P., & Noret, N. (2008). Victimization, social support, and psychosocial functioning among children of same-sex and opposite-sex couples in the United Kingdom. Developmental Psychology 44, 127 – 134. Sandberg, J. F., ...

s International, 59-A, 3662. Risman, B. J. (1987). Intimate relationships from a microstructural perspective: Men who mother. Gender and Society, 1, 6 – 32. *Rivers, I., Poteat, V. P., & Noret, N. (2008). Victimization, social support, and psychosocial functioning among children of same-sex and opposite-sex couples in the United Kingdom. Developmental Psychology 44, 127 – 134. Sandberg, J. F., ...

Since the introduction of ultrasound in cardiology, the wish to quantify cardiac function was the driver for the development of new technologies. M-mode, which projects speckle information of cardiac struc tures over time, is so to speak the initial form of one-dimensional wall motion tracking. Twodimen sional speckle tracking is useful, has some limitations, though, because the heart has three...

Hybridoma producing monoclonal antibodies (mAbs), specific for three clinically significant Pseudomonas aeruginosa (serotypes 03, 06, and Oil), were generated to investigate the prevalence of these serotypes in three Northwestern Ohio hospitals. Fusion products reacting with bacterial cells or membrane extracts were detected by enzyme-linked-immunosorbent assay (ELISA). Three mAbs designated: 7...