background and aims: the safe, potent and effective live vaccines against measles, mumps and rubella as important childhood diseases have been available for several decades. several factors can affect the thermal stability of lyophilized vaccine. methods: in this study, the effect of residual moisture on thermal stability of 61 batches of mmr vaccine was investigated using an accelerated method...

In this paper we study some monotone behavior of the residual (past) entropy of order . We prove that, under some relation between the hazard rates (reversed hazard rates) of two distributions functions F and G, when the residual (past) entropy of order of F is decreasing (increasing) then the residual (past) entropy of G is decreasing (increasing). Using this, several conclusions regarding mo...

tumor size seems to be a determinant in the prognosis of early cervical cancer. patients with tumor size greater than 4 cm (bulky) in diameter have worse outcome.' the purpose of this study was to compare the efficacy of preoperative combined chemoradiation and neoadjuvant chemotherapy (narc) programs followed by radical hysterectomy in stage ib - lib bulky cervical cancer. from september ...

In the surgical multimodal management of malignant pleural mesothelioma, it seems crucial to proceed with an efficient local adjuvant treatment to kill residual tumor cells. Intrapleural photodynamic therapy has recently emerged as a potential candidate in this goal. In this review, we analyzed and classified 16 articles in which patients with malignant pleural mesothelioma received intrapleura...

Mine tailings from an abandoned metal mine in Korea contained high concentrations of arsenic (As) and heavy metals [e.g., As: 67,336, Fe: 137,180, Cu: 764, Pb: 3,572, and Zn: 12,420 (mg/kg)]. US EPA method 6010 was an effective method for analyzing total arsenic and heavy metals concentrations. Arsenic in the mine tailings showed a high residual fraction of 89% by a sequential extraction. In To...

BACKGROUND Although some Japanese Galerina species poisonings manifest as gastrointestinal symptoms followed by late-onset hepatorenal failure (phalloides syndrome), the toxin responsible for this has not been determined. CASE REPORT We report a 6-year-old boy who developed characteristic cholera-like diarrhea and late-onset severe hepatic deterioration after eating mushrooms, later identifie...

most of the targeted heavy metals (hms) in sewage sludge ended up in solid residues after pyrolysis and gasification, such as Cu, Zn, Cr, Ni and Pb, which their residual rates were over 70%. The bioavailability of the hms in residues decreased despite their concentrations being higher compared with in sludge. The potential eco-toxicity of each HM were ceased after pyrolysis and gasification of ...

Acridine orange (AO) is a known radiation sensitizer, and concomitant local administration of AO and irradiation (5 Gy) after cytoreductive surgery results in good local control of musculoskeletal sarcomas in humans. Local administration of AO solution into the surgical field can act directly on residual tumor cells, and it is thought that systemic administration of AO may affect tumor cells in...

Honeybee, Apis mellifera, is one of the most important pollinators in the world. Since pesticides have been used widely, honeybees are unavoidable at risk exposing to various contaminated sources of residual pesticides while they are engaging foraging activities in collecting nectar and pollens. The effects of various levels of sub-lethal dosages of insecticides on the biology, development and ...

Ricin is a plant toxin that is a CDC level B biothreat. Our recombinant ricin A chain vaccine (RiVax), which contains mutations in both known toxic sites, has no residual toxicity at doses at least 800 times the immunogenic dose. RiVax without adjuvant given intramuscularly (i.m.) protected mice against intraperitoneally administered ricin. Furthermore the vaccine without alum was safe and immu...