In this paper, molybdenum nanoparticles (Mo NPs) were prepared by cold plasma method with different concentrations and time constant. Some structural tests performed using X-ray diffraction (XRD). field emission scanning electron microscopy (FESEM). energy-dispersive spectroscopy (EDX). Average crystal size is variable. Effect of the nanomaterial on growth Pseudomonas aeruginosa bacteria. The r...

The in vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against 50 Pseudomonas aeruginosa strains was studied by the broth dilution method and the time-kill curve method. The majority of the P. aeruginosa strains tested were resistant to ceftriaxone. Combining ceftriaxone with the aminoglycosides resulted in synergism, antagonism, or indifference.

Doripenem is a member of the carbapenem family of antibiotics with significant potential for use in Pseudomonas aeruginosa infections without acquired resistance. United States Food and Drug Administration (US FDA) approved indications for doripenem include treatment of complicated urinary tract infections (cUTI), complicated intra-abdominal infections (cIAI) and nosocomial pneumonia including ...

Netilmicin (Sch 20569), a semisynthetic aminoglycoside related to gentamicin C(1a), was evaluated in vitro in agar dilution testing against 224 different clinical isolates of gentamicin-resistant Enterobacteriaceae and Pseudomonas aeruginosa in parallel with amikacin, gentamicin, sisomicin, and tobramycin. Netilmicin showed a very high degree of activity against gentamicin-resistant organisms, ...

The ongoing spread of antimicrobial resistance has complicated the treatment bacterial hospital-acquired pneumonia (HAP) and ventilator-associated (VAP). Gram-negative pathogens, especially those with multidrug-resistant profiles, including Escherichia coli, Klebsiella pneumoniae, Enterobacter </ns4:bold...

Beta-lactam resistance in Pseudomonas aeruginosa detected only during ceftazidime therapy of cystic fibrosis patients was studied. Evaluation of resistant and susceptible isolates from one patient and resistant laboratory derivatives indicated that elevated beta-lactamase levels were the primary determinant of resistance. Susceptible isolates outgrew resistant isolates on antibiotic-free medium.

BACKGROUND Multidrug-resistant Pseudomonas aeruginosa has emerged as one of the most important healthcare-associated pathogens. Colistin is regarded as the last-resort antibiotic for multidrug-resistant Gram-negative bacteria, but is associated with high rates of acute kidney injury. The aim of this in vitro study is to search for an alternative treatment to colistin for multidrug-resistant P. ...

Aim: Antimicrobial resistance in bacteria is one of the most discussed and important theme healthcare field now. Bacteriophages are known as promising alternative to antibiotics a method fighting multi-resistant pathogens. In this study, our main aim was isolate lytic specific phages multidrug resistant Pseudomonas aeruginosa, dangerous bacterial human Methods: Disk-diffusion method, spot-test,...

Pseudomonas aeruginosa, an important nosocomial pathogen is difÞ cult to treat because of high antimicrobial resistance.[1] The common form of resistance is mediated by lack of drug penetration and / or carbapenem hydrolyzing ß-lactamases.[2] Detection of metallo ß lactamase (MBL)producing P. aeruginosa is crucial for the optimal treatment of patients. The present study was undertaken to study ...

The in vitro activity of a new penem antimicrobial agent, CGP 31608, was compared with those of imipenem, SCH 34343, and several other antimicrobial agents against approximately 600 bacterial isolates. CGP 31608 was active against gram-positive organisms, including methicillin-susceptible Staphylococcus aureus (MIC for 90% of the isolates [MIC90], 0.25 microgram/ml) and penicillin-susceptible s...