conclusions infection with hmpv and rsv are most frequent infections among pediatric patients with respiratory tract symptoms. coinfection with these viruses may exacerbate the clinical symptoms and increase hospitalization rates, especially in children younger than one year old. results the hmpv and rsv were detected in 44 (15.7%) and 84 (30.0%) samples, respectively. coinfection with both vir...

The distinction between bacterial and viral causes of infections of the respiratory tract is a major but important clinical challenge. We investigated the diagnostic performance of human neutrophil lipocalin (HNL) in respiratory tract infections compared to those of C-reactive protein (CRP) and procalcitonin (PCT). Patients were recruited from the emergency department and from a primary care un...

Objective: To detect and evaluate the role of the newly recognized human coronavirus (HCoV)-NL63 and HCoV-HKU1 as aetiologic agents of acute respiratory tract infections in hospitalized Jordanian children younger than 5 years of age. Methods: Between December 2003 and May 2004, a total of 326 nasopharyngeal aspirates were collected from Jordanian children hospitalized with acute respiratory tra...

Respiratory infections are the greatest single contributor to the overall burden of disease worldwide [1]. Polymicrobial infections are becoming increasingly recognized in terms of both prevalence and their effect on disease severity, causing many common diseases such as oral infections, otitis media, chronic wound infections, and implanted medical device infections, as well as chronic pulmonar...

conclusions although several studies have investigated viral respiratory co-infection, no study has evaluated the rate of respiratory co-infections in adenovirus-positive samples from children younger than 5 years. however, this study has filled this gap, the the number of co-infections were too small to draw any definite conclusions. therefore, large-scale studies using bigger samples are requ...

Introduction Doxycycline is an antibiotic belonging to the group of tetracyclines. It is active against gram positive and gram negative bacteria. It has been on the Dutch market at least since 1973 and the oral preparation is indicated for infections of the respiratory tract, infections of the urogenital tract, infections of the skin and soft tissues, Borrelia burgdorfori infections, infections...

The overuse of antibiotics in children is becoming a major public health problem. Although most of the common childhood infections such as diarrhea and upper respiratory tract infections are caused by viruses, large volumes of antibiotics are prescribed for these infections in children in the primary care settings. Excessive use of antibiotics is the fundamental risk factor for the development ...

Abstract Anelloviruses (AVs) are ubiquitous in humans and the most abundant components of commensal virome. Previous studies on diversity, transmission persistence AVs mainly focused blood or transplanted tissues from adults; however, profile anellome respiratory tract children barely known. We investigated their dynamics upper a cohort with acute infections (ARTIs). Different to that adult, be...