In the context of global change, the physiological and hormonal stress responses have received much attention because of their implications in terms of allostasis. However, most studies have focused on glucocorticoids only as the "common" response to stressors while neglecting other endocrine axes and hormones (e.g. prolactin, thyroid hormones) that play a crucial role in metabolic adjustments....

PURPOSE To determine whether voluntary exercise (wheel running) has the potential of relieving stress. METHODS In this study, restraint stress with or without voluntary wheel running was performed for mice housed in individual cages. A total of 21 ICR male mice were assigned into control (CON), restraint stress with voluntary exercise (RSVE), or restraint stress (RS) without voluntary exercis...

In this study we evaluated by telemetry the effects of ANG II and ANG-(1-7) infusion on the circadian rhythms of blood pressure (BP) and heart rate (HR) and on the cardiovascular adjustment resulting from restraint stress in rats. ANG II or ANG-(1-7) or vehicle were infused subcutaneously for 7 days. Restraint stress was carried out before, during, and after infusion at 7-day intervals. Paralle...

bstract—Chronic stress and spatial training have been proosed to affect hippocampal structure and function in oppoite ways. Previous morphological studies that addressed tructural changes after chronic restraint stress and spatial raining were based on two-dimensional morphometry which oes not allow a complete morphometric characterisation of ynaptic features. Here, for the first time in such s...

Bu çalışmada, akut kısıtlama stresi ve soğuk stresinin sıçanlarda elektrokardiyografik (EKG) parametreler üzerindeki etkilerini araştırıldı. Toplam 18 adet 8-10 haftalık, ağırlıkları 180-220 g olan erkek Wistar albino rat üç eşit gruba (n=6/grup) ayrıldı. Kontrol grubundaki ratlara stresör uygulanmadı. Kısıtlama ratlar 2 saat kısıtlayıcıda tutuldu. Soğuk tutma kısıtlayıcı içinde +4°C'de Sıçanla...

Systemic administration of cannabidiol (CBD), a non-psychotomimetic compound from Cannabis sativa, attenuates the cardiovascular and behavioral responses to restraint stress. Although the brain structures related to CBD effects are not entirely known, they could involve brainstem structures responsible for cardiovascular control. Therefore, to investigate this possibility the present study veri...

The effects of acute restraint stress on sperm motility and reproductive endocrinology were investigated in adult rats. Sperm motility was determined by computer-assisted sperm analysis. Acute restraint stress reduced sperm motility starting after 30 min, and the sperm motility parameters, percentage of motile spermatozoa (%), straight-line velocity, curvilinear velocity, deviation of the sperm...

Previous research has shown that chronic restraint stress exacerbates Theiler's virus infection, a murine model for CNS inflammation and multiple sclerosis. The current set of experiments was designed to evaluate the potential role of glucocorticoids in the deleterious effects of restraint stress on acute CNS inflammatory disease. Exposure to chronic restraint stress resulted in elevated levels...

BACKGROUND Because brain development continues during adolescence, the effects of chronic stress on hippocampal changes that occur during that period are permanent. Oxytocin, which is synthesized in the hypothalamus and has many receptors in brain regions, including the hippocampus, may affect learning-memory. This study aimed to investigate chronic restraint stress on hippocampal functions, an...

Exposure to chronic restraint (CR) modifies the hypothalamic-pituitary-adrenal (HPA) axis response to subsequent acute stressors with adaptation of the response to a homotypic and sensitization of the response to a heterotypic stressor. Since vasopressin (AVP) activity has been reported to change during chronic stress, we investigated whether this was an important factor in HPA facilitation. We...