The gene for the coagulation protein factor VIII contains several common restriction fragment length polymorphisms which can be used to analyse the pattern of inheritance of factor VIII alleles within families. This can be exploited to identify carriers of haemophilia, an X-linked inherited disorder characterised by deficiency of factor VIII. In this study the polymerase chain reaction was used...

Restriction Fragment Length Polymorphism (RFLP) is a technique in which organisms may be differentiated by analysis of patterns derived from cleavage of their DNA. If two organisms differ in the distance between sites of cleavage of a particular restriction endonuclease, the length of the fragments produced will differ when the DNA is digested with a restriction enzyme. The similarity of the pa...

Background & Aims: In recent years, molecular methods for characterizing genetic heterogeneity have found a major place in modern approaches. In this study, two different molecular techniques including Restriction Fragment Length Polymorphism (RFLP) and Multi Locus microsatellite typing (MLMT) were carried out in order to evaluate genetic heterogeneity among isolates of Leishmania major in Iran...

The results of molecular genetic analysis 13 polymorphic variants genes, according to the data genome-wide association studies (GWAS) associated with development addictive states, in group persons alcohol dependence (n = 142) and comparison 211) are presented. main genotyping method is polymerase chain reaction (PCR) followed by high resolution melting (HRM) clustering profiles; validated using...

conclusions the results of antifungal susceptibility tests demonstrated that voriconazole was the most active drug against candida isolates. candida albicans is the most common yeast isolated from human blood world-wide; the unexpectedly higher rate of c. parapsilosis isolated in this study necessitates more studies with larger sample sizes in iran. results candida parapsilosis (c. parapsilosis...

background interleukin-16 (il-16) is an immunomodulatory cytokine, which plays an important role in some inflammatory and autoimmune diseases such as hepatitis b, which is a major health concern worldwide. objectives in this study, we aimed to investigate the plausible association between il-16 polymorphism and chronic hbv susceptibility in an iranian population. conclusions these findings show...