نتایج جستجو برای: retinol binding protein

تعداد نتایج: 1449573  

Journal: :Archives of disease in childhood 1989
D M Gibb P A Tomlinson N R Dalton C Turner V Shah T M Barratt

The urinary extraction of albumin, retinol binding protein, and N-acetyl-beta-D-glucosaminidase were studied in 60 children with insulin dependent diabetes mellitus and in 45 normal children to find out whether the renal tubules played a part in causing the early increase in urinary excretion of albumin that occurs in diabetes mellitus. Two overnight urine samples were collected and the protein...

Journal: :Journal of lipid research 1987
C M Lenich A C Ross

The binding and metabolism of [3H]vitamin A-containing chylomicron (CM) remnants by the human hepatoma cell line HepG2 were studied. Mesenteric lymph chylomicrons were collected from [3H]retinol-fed rats and incubated with lipoprotein lipase to obtain CM remnants. At 4 degrees C, specific CM remnant binding was inhibited by an excess of unlabeled CM remnants. Specific binding predominated at lo...

Journal: :The Journal of biological chemistry 1982
D R Soprano J E Smith D S Goodman

Studies were conducted to explore the role of retinol in the control of the rate of synthesis of plasma retinol-binding protein (RBP) in the liver of the rat. Previous studies have shown that nutritional retinol status strongly influences RBP secretion from the liver cell. Both the in vivo relative rate of RBP synthesis and the in vitro translatable level of RBP-specific mRNA were examined in n...

Journal: :The American journal of clinical nutrition 2004
Jared M Baeten Barbra A Richardson Daniel D Bankson Mark H Wener Joan K Kreiss Ludo Lavreys Kishorchandra Mandaliya Job J Bwayo R Scott McClelland

BACKGROUND Serum retinol is the most commonly used indicator of vitamin A status. Retinol is transported in a 1-to-1 complex with retinol-binding protein (RBP). RBP is easy and inexpensive to measure, and studies have shown a high correlation between concentrations of RBP and concentrations of retinol. The performance of RBP in the context of infection or protein malnutrition, however, has not ...

Journal: :The Journal of biological chemistry 2003
Zhiping Wu Yanwu Yang Natacha Shaw Sanjoy Bhattacharya Lin Yan Karen West Karen Roth Noa Noy Jun Qin John W Crabb

Retinoid interactions determine the function of the cellular retinaldehyde binding protein (CRALBP) in the rod visual cycle where it serves as an 11-cis-retinol acceptor for the enzymatic isomerization of all-trans- to 11-cis-retinol and as a substrate carrier for 11-cis-retinol dehydrogenase (RDH5). Based on preliminary NMR studies suggesting retinoid interactions with Met and Trp residues, hu...

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