Retinopathy of Prematurity Transscleral Retinal Photocoagulation (TSRPC) The 810 nm diode laser wavelength makes lens-sparing transscleral coagulation of the retina possible, and to evaluate the efficacy and safety of transscleral diode laser coagulation for threshold ROP, the authors performed a controlled clinical study. Forty eyes of 20 preterm infants (gestational age 24-29 weeks, mean 26.8...

IMPORTANCE Measurable competence derived from comprehensive and advanced training in grading digital images is critical in studies using a reading center to evaluate retinal fundus images from infants at risk for retinopathy of prematurity (ROP). Details of certification for nonphysician trained readers (TRs) have not yet been described. OBJECTIVE To describe a centralized system for grading ...

ROP is a significant cause of blindness and an even bigger problem in the under developed world. In the developed world major advances have occurred in the diagnosis, treatment and in research. Most recent developments such as the prospective early treatment for ROP (ETROP) established the importance of proper screening and earlier treatment 1 . The treatment has advanced from cryopexy to almos...

Retinal neovascularization in retinopathy of prematurity (ROP) is the most common cause of blindness for children. Despite evidence that hypoxia inducible factor (HIF)-1α -VEGF axis is associated with the pathogenesis of ROP, the inhibitors of HIF-1α have not been established as a therapeutic target in the control of ROP pathophysiology. We investigated the hypothesis that degradation of HIF-1α...

INTRODUCTION For many decades, researchers worldwide have been investiga­ ting the causes of retinopathy of prematurity (ROP) and the best method to identify the preterm children that are at risk of developing this disease. In 2007, one ROP research group in Brazil published the criteria for se lecting premature children for examination and ROP treatment, following the assessment of regional ch...

Retinopathy of prematurity (ROP) is a leading cause of potentially avoidable childhood blindness worldwide. With improvement in neonatal care, more preterm infants are surviving with a resultant increase in the number of ROP cases. In low-middle income countries, the disease epidemiology is characterized by the occurrence of ROP at higher birthweight in premature babies with greater severity at...

Oxygen-induced oxidative stress (OS) has damaging effects in the perinatal period. For now there is a lake of evidence that OS occurs in babies with retinopathy of prematurity (ROP) We tests the hypothesis that a strict oxygen policy may minimize postnatal OS reducing severity of ROP. Multicenter prospective cohort study (72 newborns), using a common clinical management protocol with a strict c...

There have been many major advances recently that have improved the identification and management of retinopathy of prematurity (ROP). This chapter describes the clinical features of ROP and then considers briefly the incidence and epidemiology of acute phase disease. This is followed by a discussion of the two ROP epidemics and ROP-induced disability in high, low and middle income countries, a...

AIMS To study the efficacy of infrared diode laser for the treatment of posterior retinopathy of prematurity (ROP). METHODS 48 eyes of 25 premature babies (mean birth weight 779 (SD 127.7) g; mean gestational age 25.5 (SD 1.47) weeks) with threshold ROP in zone I and posterior zone II were treated by the indirect infrared (810 nm) diode laser. Confluent burns were applied to the avascular ret...

Objective To explore the etiology, incidence and methods to prevent and treat severe retinopathy of prematurity (ROP), which is rapidly becoming a threat to the vision of babies in areas of the world where increasing numbers of premature babies are surviving. Data sources The data used in this review were mainly from Medline and PubMed published in English. The search term was “retinopathy of p...