OBJECTIVES To report a new phenotype of advanced endemic goiter that affects only one lobe of the thyroid gland. PATIENTS AND METHODS This study included 60 patients from the west of Sudan with long-standing unilateral simple endemic goiter that required obectomy, with emphasis on the gross appearance, measurements and cytological features of the contralateral lobe. RESULTS Out of 60 patien...

background endemic goiter is present in most parts of iran. iron deficiency adversely affects the physiology of thyroid. the initial steps of thyroid hormone synthesis are catalyzed by thyroperoxidases and are dependent on iron. in many developing countries, children are at high risk of both goiter and iron deficiency anemia. in addition, iron deficiency may alter central nervous system control...

Dislocation of the clavicle, either at the acromial or sternal end, is much less common than fracture ; and retrosternal dislocation is so unusual that there is little reference to it in the literature. Standard text-books on fractures and dislocations ignore the condition completely, or dismiss it in a few lines. The rarity of the injury, the typical signs and symptoms, and the grave potential...

Iodine-123 single photon emission computed tomography (SPECT) imaging of the thyroid was performed in two patients with multinodular goiter and swallowing difficulty to provide the functional and anatomic orientation of the goiter in relation to the airway. Transaxial slices showed the retrolaryngeal extension of the enlarged thyroid and the tracheal compression by the goiter in both patients. ...

The aim of the present study was to estimate the prevalence of goiter in schoolchildren in a formerly iodine-deficient region in southern Brazil by assessing the relationship between body surface area (m2 ) and thyroid volume (ml) measured by ultrasonography. A population-based sample of 1,094 randomly selected schoolchildren (6 to 14 years; 556 boys and 538 girls) underwent clinical evaluation...

Epidemiology Goiter: In iodine-deficient areas, goiter prevalence may be as high as 80%. After correction of iodine deficiency, prevalence decreases slowly over a generation’s time to but not below a few per cent. In iodine-sufficient areas, cross-sectional studies showed a decline in frequency of diffuse goiter and, in contrast, an increase of thyroid nodules and thyroid antibodies with age. F...

Retrosternal goitre is defined as a goitre with a portion of its mass > or = 50% located in the mediastinum. Surgical removal is the treatment of choice and, in most cases, the goitre can be removed via a cervical approach. Aim of this retrospective study was to analyse personal experience in the surgical management of retrosternal goitres, defining, in particular, the features requiring sterno...