In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

polydimethylsiloxane (pdms) has been synthesized by ring-opening polymerization of octamethylcyclotetrasiloxane (d4) in microemulsion with acidic catalyst. the structure and properties of microemulsion were characterized by transmission electron microscopy (tem), fourier transform infrared spectroscopy (ft-ir), photo correlation spectroscopy (pcs). the effect of the variation in ph value, amoun...

Microemulsions improve the transdermal delivery of several drugs over conventional topical preparations such as emulsions and gels: enhanced drug solubilization, increased skin flux, decreased diffusion coefficient. Microemulsion-based systems find significant improvement in antifungals. We believe that drug-loaded microemulsion will show better antifungal activity by penetration into fungal ce...

The paper is focused on the formation of calcium phosphate nanoparticles (CP) in polyelectrolyte-modified microemulsions, in a microemulsion template phase consisting of cyclohexane, water, anionic surfactantant and cosurfactant, in the presence of anionic and cationic polyelectrolyte. It is shown that polyelectrolyte, can be incorporated into the individual inverse microemulsion droplets. The ...

The paper is focused on the formation of hydroxyapatite nanoparticles (HAp) in polyelectrolyte-modified microemulsions, in a microemulsion template phase consisting of cyclohexane, water, cationic surfactant and cosurfactant, in the presence of Na-polyacrylate (PAA) as an anionic polyelectrolyte. It is shown that PAA, can be incorporated into the individual inverse microemulsion droplets. The m...

The paper is focused on the formation of calcium phosphate nanoparticles (CP) in polyelectrolyte-modified microemulsions, in a microemulsion template phase consisting of cyclohexane, water, anionic surfactantant and cosurfactant, in the presence of anionic and cationic polyelectrolyte. It is shown that polyelectrolyte, can be incorporated into the individual inverse microemulsion droplets. The ...

Microemulsion based cyclosporine has demonstrated better absorption with laser pharmacokinetic variability. For the clinical use of any new microemulsion based product, bioequivalence testing with existing formulation is necessary. Panimun Bioral (Test) and Sandimmun Neoral (Reference) were evaluated in different transplant centers using both volunteers as well as renal transplant patients. All...

The paper is focused on the formation of hydroxyapatite nanoparticles (HAp) in polyelectrolyte-modified microemulsions, in a microemulsion template phase consisting of cyclohexane, water, cationic surfactant and cosurfactant, in the presence of Na-polyacrylate (PAA) as an anionic polyelectrolyte. It is shown that PAA, can be incorporated into the individual inverse microemulsion droplets. The m...